Ashwagandha Extract 1000mg 180 Tablets UK Made. Pharmaceutical Grade Supplement, Mood Stress

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Bhattacharya, S. K. and Muruganandam, A. V. Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress. Pharmacol Biochem.Behav 2003;75(3):547-555. View abstract. Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9. View abstract. Those who took the ashwagandha supplements also saw improvements in sleep quality compared with the placebo group. Dhuley, J. N. Therapeutic efficacy of Ashwagandha against experimental aspergillosis in mice. Immunopharmacol.Immunotoxicol. 1998;20(1):191-198. View abstract.

This powerful herb can help a wide range of conditions and symptoms, such as anxiety, restlessness, high blood pressure and fatigue. So if you’re looking to increase your energy, improve your mood and fight the effects of aging, what is the proper ashwagandha dosage? Ashwagandha contains numerous bioactive compounds, namely alkaloids, flavonoids, glycosides, steroids, and steroidal lactones. [10] Within the steroidal lactones are withanolides, which are considered to be responsible for most of the plant’s benefits. Ashwagandha may also provide reproductive benefits for men. Administering ashwagandha to infertile men has shown to improve sperm quality significantly by rebalancing reproductive hormone levels [11] Gupta A, Mahdi AA, Shukla KK, et al. Efficacy of Withania somnifera on seminal plasma metabolites of infertile males: a proton NMR study at 800 MHz. J Ethnopharmacol. 2013;149(1):208-214. . After one study, 14% of the male patients’ partners became pregnant [12] Mahdi AA, Shukla KK, Ahmad MK, et al. Withania somnifera Improves Semen Quality in Stress-Related Male Fertility [published online ahead of print, 2009 Sep 29]. Evid Based Complement Alternat Med. 2009;2011:576962. . Devi, P. U., Sharada, A. C., and Solomon, F. E. In vivo growth inhibitory and radiosensitizing effects of withaferin A on mouse Ehrlich ascites carcinoma. Cancer Lett. 8-16-1995;95(1-2):189-193. View abstract.

At least one clinical study indicates ashwagandha can benefit women experiencing sexual dysfunction [10] Dongre S, Langade D, Bhattacharyya S. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study. Biomed Res Int. 2015;2015:284154. . The administration of ashwagandha resulted in significant improvements in arousal, lubrication, orgasm and satisfaction, as self-reported by the participants. It also significantly improved the number of successful sexual encounters and improved metrics of distress around their sex lives and sexuality. 5. Boosts Fertility and Testosterone Levels in Men Since withanolides are considered to be the major active component in ashwagandha, some extracts are standardized to contain a certain or minimum amount. Clinical trials have used standardized extracts containing anywhere from 1.5% to 35% withanolides, [1] [2] [3] [4] [5] [6] [7] but many studies do not disclose this information and the optimal amount of withanolides is not yet clear. Note that while studies may use standardized extracts or proprietary formulas, variations in extraction methods, formulation, or composition can affect physiological response. Agarwal R, Diwanay S, Patki P, Patwardhan B. Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation. J Ethnopharmacol 1999;67:27-35. View abstract. Kamal HI, Patel K, Brdak A, Heffernan J, Ahmad N. Ashwagandha as a unique cause of thyrotoxicosis presenting with supraventricular tachycardia. Cureus. 2022 Mar 25;14(3):e23494. View abstract. Bonilla DA, et al. (2021). Effects of ashwagandha ( Withania somnifera) on physical performance: Systematic review and Bayesian meta-analysis.

One 2015 study in humans suggested that ashwagandha root extract could enhance a person’s cardiorespiratory endurance, which could improve heart health. However, more research is necessary. Alzheimer’s treatment Khattak, S., Saeed, Ur Rehman, Shah, H. U., Khan, T., and Ahmad, M. In vitro enzyme inhibition activities of crude ethanolic extracts derived from medicinal plants of Pakistan. Nat.Prod.Res 2005;19(6):567-571. View abstract. Bhattacharya SK, Satyan KS, Ghosal S. Antioxidant activity of glycowithanolides from Withania somnifera. Indian J Exp Biol 1997;35:236-9. View abstract. Devpura G, et al. (2021). Randomized placebo-controlled pilot clinical trial on the efficacy of ayurvedic treatment regime on COVID-19 positive patients. O'Connor J, Lindsay K, Baker C, Kirby J, Hutchins A, Harris M. The impact of ashwagandha on stress, sleep quality, and food cravings in college students: quantitative analysis of a double-blind randomized control trial. J Med Food 2022. View abstract.

Kulkarni, S. K. and Dhir, A. Withania somnifera: an Indian ginseng. Prog.Neuropsychopharmacol.Biol.Psychiatry 7-1-2008;32(5):1093-1105. View abstract. Björnsson HK, Björnsson ES, Avula B, et al. Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020;40(4):825-829. View abstract. With so many Ashwagandha supplements on the market, it can be challenging to choose the best one. Look for supplements that are standardized to contain withanolides, which are believed to be the primary active compounds in Ashwagandha. Additionally, choose supplements that are made from high-quality and organic Ashwagandha roots to ensure purity and potency. Finally, always follow the recommended dosage on the product label and store supplements in a cool, dry place away from sunlight and heat.

Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol 1998;50:1065-68. View abstract. Ashwagandha supplements are made from the roots of the Ashwagandha plant which are dried and crushed into a powder or made into capsules. Ashwagandha supplements come in various strengths, with 1000mg being a commonly recommended dose. Ashwagandha contains a group of compounds called withanolides, which are believed to be responsible for its health benefits. Withanolides have been studied for their potential to reduce inflammation, improve immune function, and protect against oxidative stress. In particular, withanolide A and withaferin A have been shown to have anti-cancer properties. Ashwagandha’s potential anti-cancer properties are an area of ongoing research, and while more studies are needed, initial findings are promising. Ashwagandha extracts have been shown to inhibit the growth and spread of cancer cells in test tubes and animal studies. Additionally, withanolides have been shown to have anti-angiogenic effects, meaning that they can help prevent the formation of new blood vessels that cancer cells need to grow. Withanolide A and withaferin A, in particular, have been shown to have potent anti-cancer effects, and researchers are hopeful that Ashwagandha may one day be used as a complementary treatment for various types of cancer. Are you looking for a natural way to boost your overall health and wellbeing? Then you may want to consider taking Ashwagandha 1000mg, also known as Withania somnifera or Winter Cherry. This herb has been used for centuries in traditional Ayurvedic medicine for its various health benefits. In this comprehensive guide, we will explore the different aspects of this herb, from its history and traditional uses to its potential health benefits, safety profile, and recommended dosage. Introduction to Ashwagandha Studies on ashwagandha have used daily dosages ranging from 120–5,000 mg of a root extract. The most common dosing protocol is 600 mg daily, divided into two doses, with one taken in the morning with breakfast and the other in the evening.

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Lubarska M, Halasinski P, Hryhorowicz S, et al. Liver Dangers of Herbal Products: A Case Report of Ashwagandha-Induced Liver Injury. Int J Environ Res Public Health 2023;20(5):3921. View abstract. Akabas SR, Vannice G, Atwater JB, et al. Quality certification programs for dietary supplements. Journal of the Academy of Nutrition and Dietetics. 2016;116(9):1378-1379.doi:10.1016/j.jand.2015.11.003 It’s important to talk to your healthcare provider before starting any new supplement, including Ashwagandha. They can help you determine the appropriate dosage and ensure that it won’t interact with any medications you’re currently taking. Additionally, if you experience any negative side effects while taking Ashwagandha, such as upset stomach or dizziness, stop use and consult your healthcare provider. Conclusion: Is Taking Ashwagandha 1000mg Right for You? Ashwagandha is best known for its anxiolytic (anti-anxiety) and stress-relieving effects. [16] [17] [18] [19] [20] It also seems to reduce cortisol levels. [8] [21] [18] [19] [22] [20] In addition, a growing body of evidence supports the efficacy of ashwagandha for improving total sleep time and sleep quality in people with and without insomnia. [5]

Pusec CM, Wolsky R, Llerena C, Sura P. A Case of Supplement-Induced Hepatitis. Cureus 2022;14(10):e30433. View abstract.Women may benefit from taking Ashwagandha supplements due to its potential effects on hormone regulation. Ashwagandha has been shown to increase testosterone levels in men, and while more research is needed, it may also have similar effects in women. Additionally, Ashwagandha has been used traditionally to regulate menstrual cycles and relieve symptoms of menopause, such as hot flashes and mood swings. More research is needed in this area. Bhattacharya, S. K., Bhattacharya, A., Sairam, K., and Ghosal, S. Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Phytomedicine 2000;7(6):463-469. View abstract.