GALPHARM Diarrhoea Relief Instant Melts 2mg Loperamide Orodispersible Tablets 6's X 2

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The orodispersible tablets should be placed on the tongue. The tablet will dissolve and is to be swallowed with saliva. No liquid intake is needed for theorodispersible tablet. Do not use this medicine after the expiry date which is stated on the blister and box. Theexpiry date refers to the last day of that month. In particular tell your doctor or pharmacist if you are taking, have recently taken or might take anyof the following medicines: headaches – make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller. Talk to your doctor if the headaches last longer than a week or are severe. you are constipated, or your stomach appears swollen (especially in children with severe dehydration),

The recommended dose depends on the type of diarrhoea you have and your age. Adults (over 18), with short-term diarrhoea or IBS A limited amount of data from the use of loperamide in pregnant women is available. In one of two epidemiological studies the use of loperamide during early pregnancysuggested a possible moderate increased risk for hypospadia, however, an increasedrisk for major malformations could not be identified. Animal studies do not indicatedirect or indirect harmful effects with respect to reproductive toxicity (see section5.3). If you have AIDS and your stomach becomes swollen. Stop taking the tablets immediately and talk to your doctor.Loperamide hydrochloride is a synthetic opioid which inhibits gut motility by binding to opiate receptors in the gut wall and may also reduce gastrointestinal secretions,resulting in improvement in diarrhoea symptoms. constipation – stop taking loperamide. If you have constipation, eat more fibre by having fresh fruit, vegetables and cereals, and drink plenty of water. Try to exercise regularly, for example by going for a daily walk or run. If this does not help, talk to your pharmacist or doctor.

Peppermint Flavour Silica, Colloidal AnhydrousSilica, Colloidal HydratedStarch, PregelatinisedSucralose 6.2 Incompatibilities Superdrug Diarrhoea Relief Instant-Melts 2 mg Orodispersible Tablets Tesco Anti-Diarrhoea Instants 2 mg Orodispersible TabletsNumark Diarrhoea Relief Instants 2 mg Orodispersible TabletsSainsbury’s Healthcare Anti-Diarrhoea Instants 2 mg Orodispersible Tablets 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Talk to your pharmacist before taking this medicine if you are taking any othermedicines, particularly the following: Loperamide hydrochloride should not be used alone in acute dysentery, which is characterised by blood in stools and elevated body temperatures. 4.4 Special warnings and precautions for useAlthough no pharmacokinetic data are available in patients with hepatic impairment, loperamide should be used with caution in such patients becauseof reduced first pass metabolism. (see 4.4 special Warnings and Specialprecautions for use). In a double blind randomised clinical trial in 56 patients with acute diarrhoea receiving loperamide, onset of anti-diarrhoeal action was observed within one hourfollowing a single 4 mg dose. Clinical comparisons with other antidiarrhoeal drugsconfirmed this exceptionally rapid onset of action of loperamide. 5.2 Pharmacokinetic properties Superdrug Diarrhoea Relief Instant-Melts 2mg Orodispersible Tablets contain Loperamide Hydrochloride which is an anti-diarrhoeal medicine which helps to stop diarrhoea by making the stools more solid and less frequent.

The concomitant administration of loperamide (16mg single dose) and ketoconazole, an inhibitor of CYP3A4 and p-glycoprotein, resulted in a 5-fold increase inloperamide plasma concentrations. This increase was not associated with increasedpharmacodynamic effects as measured by pupillometry. The tablets also contain simeticone, which breaks up the trapped wind in the bowel thatpauses cramps and bloating. What you need to know before you take Galpharm DiarrhoeaRelief Plus 2 mg / 125 mg Tablets Only high doses of loperamide hydrochloride affected female fertility in non-clinical studies (see section 5.3). 4.7 Effects on ability to drive and use machines Do not take loperamide for more than 48 hours without talking to a doctor. Adults (over 18) with long-lasting or recurring diarrhoea If patients are taking this medicine to control episodes of diarrhoea associated with Irritable Bowel Syndrome previously diagnosed by their doctor, and clinicalimprovement is not observed within 48 hours, the administration of loperamide HClshould be discontinued and they should consult with their doctor. Patients shouldalso return to their doctor if the pattern of their symptoms changes or if the repeatedepisodes of diarrhoea continue for more than two weeks.Allergic reactions including unexplained wheezing, shortness of breath, or swelling of the face and throat. It comes as tablets, including tablets that melt on your tongue, capsules and a liquid. The liquid is only available on prescription. The tablets that melt are called Imodium Instants or Imodium Instant Melts

Adults and children of 12 years and over with short term diarrhoea: 2 tablets to start with. After that, take 1 tablet after each loose bowel movement. Do not take more than 6 tablets in any 24 hours. Don’t take for more than 48 hours. Tablets that melt in your mouth: put the tablet on your tongue and let it melt in your saliva. You can then swallow it without a drink. Do not chew it.Boots Diarrhoea Relief Instant-Melts 2 mg Orodispersible Tablets Entrocalm Instants Diarrhoea Relief 2 mg Orodispersible Tablets Galpharm Diarrhoea Relief Instants 2mg Orodispersible Tablets Since persistent diarrhoea can be an indicator of potentially more serious conditions, loperamide hydrochlorideshould not be used for prolonged periods until theunderlying cause of the diarrhoea has been investigated. you have acute dysentery, thesymptoms of which may include bloodin your stools and a high temperature, In an 18-month carcinogenicity study in rats, with doses up to 100 times the maximum human dose no evidence of carcinogenesis was found. 6 PHARMACEUTICAL PARTICULARS 6.1 List of excipients If a doctor prescribes loperamide for your child, they will use their weight or age to work out the right dose. The dose also depends on their symptoms. What if I forget to take it?