Bells Kilkof Oral Solution for Relief of Coughs, Colds and Sore Throats 100ml - Pack of 6

Product Information

Each 4 ml contains: Cetylpyridinium Chloride BP 1.5mg, Benzoin Tincture BPC 1973 0.083ml, Ipecacuanha Tincture BP 0.1ml, Capsicum Tincture BPC 1973 0.022ml. Overdose is expected to result in effects similar to the adverse effects that are ordinarily associated with the use of diphenhydramine, including drowsiness, hyperpyrexia, and anticholinergic effects, among others . Additional symptoms during overdose may include mydriasis, fever, flushing, agitation, tremor, dystonic reactions, hallucinations and ECG changes . Large overdose may cause rhabdomyolysis, convulsions, delirium, toxic psychosis, arrhythmias, coma and cardiovascular collapse . Moreover, with higher doses, and particularly in children, symptoms of CNS excitation including hallucinations and convulsions may appear; with massive doses, coma or cardiovascular collapse may follow . Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances. Unwanted Food or Drink Products - Once supply conditions are broken, there are a number of factors outside of our control that can affect the quality of a product. Therefore perishable goods such as food and drink cannot be returned.

Dailymed."ORAJLE ANTI-BACTERIAL RINSE FOR BLEEDING GUMS (CETYLPYRIDINIUM CHLORIDE) LIQUID [CHURCH & DWIGHT CO., INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018). The results of a review on the use of diphenhydramine in renal failure suggest that in moderate to severe renal failure, the dose interval should be extended by a period dependent on Glomerular filtration rate (GFR) . Citric Acid Monohydrate contains the active ingredient Citric Acid Monohydrate which helps to reduce the dry cough and soothes the throat from any related discomfort and pain. Citric Acid is a demulcent which relieves irritation of the mucous membrane in the throat by forming a protective film. Citric Acid is absorbed after oral administration. It is found naturally in the body and is widely distributed. Furthermore, H1 receptors are similar to muscarinic receptors . Consequently, diphenhydramine also acts as an antimuscarinic . It does so by behaving as a competitive antagonist of muscarinic acetylcholine receptors, resulting in its use as an antiparkinson medication . Ultimately, diphenhydramine functions as an inverse agonist at H1 receptors, and subsequently reverses effects of histamine on capillaries, reducing allergic reaction symptoms . Moreover, since diphenhydramine is a first-generation antihistamine, it readily crosses the blood-brain barrier and inversely agonizes the H1 CNS receptors, resulting in drowsiness, and suppressing the medullary cough center .After intravenous administration of 0.8 mg/kg diphenhydramine, a prolonged half-life was noted in patients with chronic liver disease which correlated with the severity of the disease . However, the mean plasma clearance and apparent volume of distribution were not significantly affected .

We can dispense NHS repeat dispensing prescriptions issued by your doctor. Ask us for more information about this service. We operate a complaints procedure as part of the NHS system for dealing with complaints. Our system meets national criteria. Our Pharmacist will give you further information. Diphenhydramine predominantly works via the antagonism of H1 (Histamine 1) receptors . Such H1 receptors are located on respiratory smooth muscles, vascular endothelial cells, the gastrointestinal tract (GIT), cardiac tissue, immune cells, the uterus, and the central nervous system (CNS) neurons . When the H1 receptor is stimulated in these tissues it produces a variety of actions including increased vascular permeability, promotion of vasodilation causing flushing, decreased atrioventricular (AV) node conduction time, stimulation of sensory nerves of airways producing coughing, smooth muscle contraction of bronchi and the GIT, and eosinophilic chemotaxis that promotes the allergic immune response . You may also seek advice from the local Patient Advice and Liaison Service (PALS). PALS are not part of the complaints procedure itself but they might be able to resolve your concerns informally or they can tell you more about the complaints procedure and independent complaints advocacy services:

Clearance

For reasons of hygiene and safety, personal grooming products, cosmetics or items of intimate clothing cannot be returned. Capsicum Tincture 0.022ml, Benzoin Tincture 0.083ml and Cetylpyridinium Chloride 1.5mg per 5ml. Liquorice Extract, Acetic Acid E260, Tolu Tincture, Ether, Star Anise Oil, Honey, Treacle, Caramel E150c, Sucrose, Glucose, ethylhydroxybenzoate E218,Xanthan Gum E415 and Purified Water.

Reporting of side effects: If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this label. You can also report side effects directly via the Yellow Card Scheme at:ww.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine. Centers for Disease Control and Prevention (CDC). Breastfeeding and special circumstances: influenza (flu).

Babies And Small Children

We comply with the Data Protection Act and the NHS code of practice on confidentiality. If you want to discuss the records we keep, please ask to speak to the pharmacist. Treacle, Honey, Liquid Glucose, Sucrose, Tolu Tincture, Caramel (E150(c)), Liquorice Liquid Extract, Chloroform, Acetic Acid, Anaesthetic Ether, Anise Oil, Methylparaben (E218), Xantham Gum (E145) and Purified Water.