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N00.00108: Coarse-grained molecular dynamics simulations of interfacial structure and mixing in ionomer melts N00.00065: Solute Diffusivity and Local Free Volume in Cross-Linked Polymer Network: Implication of Optimizing the Conductivity of Polymer Electrolyte Buhrman H, Chandran N, Fehr S, Gelles R, Goyal V, Ostrovsky R, Schaffner C (2014) Position-based quantum cryptography: impossibility and constructions. SIAM J Comput 43(1):150–178. 10.1137/130913687 Veglia, F., Sanseviero, E. & Gabrilovich, D. I. Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity. Nat. Rev. Immunol. 21, 485–498 (2021). N00.00022: Freeze-Burn: Fabrication of Porous Carbon Networks via Polymer-Templated Rapid Thermal Annealing

Erdong Chang - Poplar, England, United Kingdom - LinkedIn

We recapitulated two major continuum states during inflammation-driven epithelial carcinogenesis: (1) genomic stable stage (CNV –/low) with inflammatory adaptation 58; (2) genomic unstable (CNV high) stage with inflammatory reprogramming 7, as epitomized by the convergence of epithelial plasticity between inflamed and malignant gallbladder epithelium. Two PBM-associated benign EPC subsets (nEPC05–06), awash with regurgitated pancreatic juice, exhibited gastrointestinal metaplastic signatures. Cluster nEPC05 largely arose from tumor samples, likely implying a pre-malignant stage with not yet developed genomic instability. Another two XGC-associated clusters displayed EMP signatures, which accounted for the associated gallbladder wall destruction and inflammatory liver invasion (CC6). Unexpectedly, we captured genomic instability in a small fraction of epithelial cells from the histologically inflamed gallbladder (CC1), implying that CNV potentially occurred early and heralded morphologically malignant transformation, mirrored by previous pan-cancer evidence 59, and meanwhile suggesting fluid boundaries between chronic inflammation and tumorigenesis stages, presumably with a transitional zone of field cancerization 60. Of note, based on IHC validation and experimental exploration, we corroborated that elevated expression of PLA2G2A was associated with GBC initiation, corresponding with the notion that PLA2G2A may display an initial beneficial effect against gastrointestinal mucosal inflammation whereas face the tradeoff of increased cancer risk 22. In such a way, PLA2G2A potentially wires long-term chronic cholecystitis up to GBC.

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Baryshev SV, Wang E, Jing C, Jabotinski V, Antipov S, Kanareykin AD, Belomestnykh S, Ben-Zvi I, Chen L, Wu Q, Li H, Sumant AV (2021) Cryogenic operation of planar ultrananocrystalline diamond field emission source in SRF injector. Applied Physics Letters 118:053505. doi: 10.1063/5.0013172 Tianyu Yuan, Tianyu Yuan, Hao Yan, Mary Lou P Bailey, Jessica F Williams, Ivan Surovtsev, Megan C King, Simon G Mochrie Brian Y Lee, Janet Y Sheung, Jonathan Garamella, Stella Kahl, Ryan J McGorty, Rae M Robertson-Anderson Fawkner-Corbett, D. et al. Spatiotemporal analysis of human intestinal development at single-cell resolution. Cell 184, 810–826.e23 (2021). N00.00116: Morphology, mechanical properties, and intermolecular interactions of ion gels based on phosphonic acid polymers

Erdong Xu - The George Washington University - LinkedIn Erdong Xu - The George Washington University - LinkedIn

N00.00061: High Conductive, Adhesive, Flexible Dual-cured Hybrid Ion-gel Polymer Electrolyte for Self-powered Energy Storage Device to Apply on Electric Vehicles N00.00164: Effect of Ionic Strength on Foaming Behaviors of Per- and Polyfluoroalkyl Substances (PFAS) Solutions Sugihara R, Gupta RK (2011) Sensor localization with deterministic accuracy guarantee. In: INFOCOM, pp 1772–1780 Cytotoxicity and exhaustion signatures were derived from differentially expressed genes across all CD8 + T cell subtypes. Pearson correlation between the reference gene GZMK (cytotoxicity signature) or HAVCR2 (exhaustion signature) and all other genes across CD8 + T cells using scaled expression values was analyzed. The top 30 genes having the highest correlation with the reference genes ( GZMK or HAVCR2) were defined as cytotoxicity and exhaustion signature genes, respectively. For CD4 + T cells, the IL2RA gene was chosen as the reference gene for defining the Treg signature using the same method. We computed signature scores for individual cells using AddModuleScore function in Seurat. WES analysis Wu, H. et al. Lipid droplet-dependent fatty acid metabolism controls the immune suppressive phenotype of tumor-associated macrophages. EMBO Mol. Med. 11, e10698 (2019).N00.00030: A mesoscale approach to model polyethylene degradation under a local temperature gradient N00.00217: Average outpouring velocity and flow rate of grains discharged from a tilted quasi-2D silo Zhang, Q. et al. Landscape and dynamics of single immune cells in hepatocellular carcinoma. Cell 179, 829–845.e20 (2019).