BioLite Charge Series PD (Charge 40 PD)

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PD is a common neurodegenerative disease. The cause of PD is still unclear, and the progress of the disease cannot be stopped with existing medical methods. Although there is currently no cure for PD, effective treatment can significantly improve patients' quality of life 1, 2. With the rapid development of high-throughput sequencing data, many diseases have entered the stage of molecular diagnosis and treatment, and it also brings the possibility of curing some intractable diseases. Many biomarkers associated with Parkinson’s disease have been discovered: SNCA was the first gene found to be associated with Parkinson’s disease, and SCNA mutations increase the risk of sporadic Parkinson’s disease 3, 4. PRKN is a gene associated with autosomal recessive Parkinson’s disease 5, 6. LRRK2 is a related gene that causes autosomal dominant PD 7, 8. In addition, many biomarkers have been discovered and used in the treatment of Parkinson's disease, which plays an important role in the improvement of the diagnosis and treatment of Parkinson’s disease 9, 10, 11, 12. However, studies have also shown that the effects of many gene mutations may be related to race, which makes certain genes not universally applicable to the diagnosis and treatment of Parkinson's disease 13, 14, 15. Therefore, it is urgent to search for more biomarkers. N460 Reasons for allowing or refusing permission to appeal (including referral to the Court of Appeal (civil division)) Berland JE, Wilson ME, Saunder RB. Results of large (8-9mm) bilateral lateral rectus muscle recessions for exotropia. Binocul Vis Strabismus. 1998;13(2):97–104.

Kanehisa, M., Furumichi, M., Sato, Y., Kawashima, M. & Ishiguro-Watanabe, M. KEGG for taxonomy-based analysis of pathways and genomes. Nucleic Acids Res. 51(D1), D587–D592 (2023). Here in we defined surgical success according to the distant angle of deviation. The goal of surgery was initial orthotropia for distance postoperatively rather than overcorrection at near distance. A lower range of distant angle measurement was detected in group E than group S p = (0.288,0.764) after 6 month and after 18 months respectively. Swallowing problems. You may develop difficulties with swallowing as your condition progresses. Saliva may accumulate in your mouth due to slowed swallowing, leading to drooling. Kim IG, Parks M, Lee SJ. Factors Associated with the Direction of Ocular Deviation in Sensory. Horizontal Strabismus and Unilateral Organic Ocular Problems. Korean J Ophthalmol. 2012;26(3):199–202.Santaella, A. et al. Inflammation biomarker discovery in Parkinson’s disease and atypical parkinsonisms. BMC Neurol. 20(1), 26 (2020). Yoon KC, You IC, Park YG. Clinical analysis of sensory strabismus. J Korean OphthalmolSoc. 2002;43:2483–8.

Gama, R. L. et al. Risk factors for visual hallucinations in patients with Parkinson’s disease. Neurol. Res. 37, 112–116 (2015).

Parkinson's disease

Isaacson SH, et al. Blinded SAPS-PD assessment after 10 weeks of pimavanserin treatment for Parkinson's disease psychosis. Journal of Parkinson's Disease. 2020; doi:10.3233/JPD-202047.