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Chocolate derived from cocoa beans contains a small amount of caffeine. The weak stimulant effect of chocolate may be due to a combination of theobromine and theophylline, as well as caffeine. [237] A typical 28-gram serving of a milk chocolate bar has about as much caffeine as a cup of decaffeinated coffee. By weight, dark chocolate has one to two times the amount of caffeine as coffee: 80–160mg per 100g. Higher percentages of cocoa such as 90% amount to 200mg per 100g approximately and thus, a 100-gram 85% cocoa chocolate bar contains about 195mg caffeine. [221] Tablets No-Doz 100mg caffeine tablets Grgic J, Trexler ET, Lazinica B, Pedisic Z (2018). "Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis". Journal of the International Society of Sports Nutrition. 15: 11. doi: 10.1186/s12970-018-0216-0. PMC 5839013. PMID 29527137.
The amount of caffeine in food and drinks varies. For example, an espresso has more caffeine than instant coffee. Similarly, dark chocolate has more caffeine than milk chocolate. Source The earliest credible evidence of either coffee drinking or knowledge of the coffee plant appears in the middle of the fifteenth century, in the Sufi monasteries of the Yemen in southern Arabia. [249] From Mocha, coffee spread to Egypt and North Africa, and by the 16th century, it had reached the rest of the Middle East, Persia and Turkey. From the Middle East, coffee drinking spread to Italy, then to the rest of Europe, and coffee plants were transported by the Dutch to the East Indies and to the Americas. [250] Schmidt B, Anderson PJ, Doyle LW, Dewey D, Grunau RE, Asztalos EV, Davis PG, Tin W, Moddemann D, Solimano A, Ohlsson A, Barrington KJ, Roberts RS (January 2012). "Survival without disability to age 5 years after neonatal caffeine therapy for apnea of prematurity". JAMA. 307 (3): 275–82. doi: 10.1001/jama.2011.2024. PMID 22253394. Caffeine sometimes increases the effectiveness of some medications, such as those for headaches. [159] Caffeine was determined to increase the potency of some over-the-counter analgesic medications by 40%. [160] Caffeine may also strengthen hair structure, including the roots and hair shaft, reducing the amount of breakage on your scalp. Improves scalp healthThis combination further stimulates the brain and promotes a state of arousal, alertness, and focus. Because it affects your brain, caffeine is often referred to as a psychoactive drug. When you drink alcohol with caffeine, the caffeine can hide some of the effects of the alcohol. This can cause you to drink more and lead to more risk-taking behaviours. It may also increase blood adrenaline levels and increase brain activity of the neurotransmitters dopamine and norepinephrine ( 3).
Some textbooks state that caffeine is a mild euphoriant, [104] [105] [106] while others state that it is not a euphoriant. [107] [108] Nehlig A (2010). "Is caffeine a cognitive enhancer?" (PDF). Journal of Alzheimer's Disease. 20 (Suppl 1): S85–94. doi: 10.3233/JAD-2010-091315. PMID 20182035. S2CID 17392483. Archived from the original (PDF) on 31 January 2021. Caffeine does not usually affect performance in learning and memory tasks, although caffeine may occasionally have facilitatory or inhibitory effects on memory and learning. Caffeine facilitates learning in tasks in which information is presented passively; in tasks in which material is learned intentionally, caffeine has no effect. Caffeine facilitates performance in tasks involving working memory to a limited extent, but hinders performance in tasks that heavily depend on this, and caffeine appears to improve memory performance under suboptimal alertness. Most studies, however, found improvements in reaction time. The ingestion of caffeine does not seem to affect long-term memory.... Its indirect action on arousal, mood and concentration contributes in large part to its cognitive enhancing properties. The central ingredient in Alpecin shampoo is caffeine. Studies show that caffeine can stimulate hair follicles and promote new hair growth in people suffering from hair loss and male pattern baldness (androgenic alopecia).
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Alpecin Double-Effect Caffeine Shampoo was developed for oily dandruff. These somewhat larger, plaque-like dandruff flakes are the result of a greasy scalp. In the first step, Alpecin Double-Effect Caffeine Shampoo loosens the crusted cells of the horny layer and thoroughly frees the scalp of dandruff. The effective anti-dandruff agents salicylic acid and piroctone olamine prevent the formation of new dandruff. In the second step, the caffeine complex recharges the hair with energy.
Smoking tobacco increases caffeine clearance by 56%. [156] Cigarette smoking induces the cytochrome P450 1A2 enzyme that breaks down caffeine, which may lead to increased caffeine tolerance and coffee consumption for regular smokers. [157] Birth control a b "Caffeine". ChemSpider. Royal Society of Chemistry. Archived from the original on 14 May 2019 . Retrieved 16 October 2014. Experimental Melting Point: You have many choices besides Alpecin when it comes to preventing hair loss. Below are some products and areas of treatment you might consider: Snel J, Lorist MM (2011). "Effects of caffeine on sleep and cognition". Human Sleep and Cognition Part II - Clinical and Applied Research. Progress in Brain Research. Vol.190. pp.105–17. doi: 10.1016/B978-0-444-53817-8.00006-2. ISBN 978-0-444-53817-8. PMID 21531247.
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a b Wikoff D, Welsh BT, Henderson R, Brorby GP, Britt J, Myers E, etal. (November 2017). "Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children". Food and Chemical Toxicology (Systematic review). 109 (Pt 1): 585–648. doi: 10.1016/j.fct.2017.04.002. PMID 28438661. If you are pregnant or breastfeeding, it’s a good idea to limit your intake of caffeine to 200mg per day. That is 1 espresso, or 2 instant coffees or 4 cups of tea. High caffeine consumption in energy drinks (at least 1 liter or 320mg of caffeine) was associated with short-term cardiovascular side effects including hypertension, prolonged QT interval, and heart palpitations. These cardiovascular side effects were not seen with smaller amounts of caffeine consumption in energy drinks (less than 200mg). [79] Severe intoxication
Extraction of caffeine from coffee, to produce caffeine and decaffeinated coffee, can be performed using a number of solvents. Following are main methods: Decaffeinated" coffees do in fact contain caffeine in many cases– some commercially available decaffeinated coffee products contain considerable levels. One study found that decaffeinated coffee contained 10mg of caffeine per cup, compared to approximately 85mg of caffeine per cup for regular coffee. [208] Detection in body fluidsCaffeine is a central nervous system stimulant that may reduce fatigue and drowsiness. [12] At normal doses, caffeine has variable effects on learning and memory, but it generally improves reaction time, wakefulness, concentration, and motor coordination. [52] [53] The amount of caffeine needed to produce these effects varies from person to person, depending on body size and degree of tolerance. [52] The desired effects arise approximately one hour after consumption, and the desired effects of a moderate dose usually subside after about three or four hours. [7] Gupta V, Lipsitz LA (October 2007). "Orthostatic hypotension in the elderly: diagnosis and treatment". The American Journal of Medicine. 120 (10): 841–7. doi: 10.1016/j.amjmed.2007.02.023. PMID 17904451. The biosynthesis of caffeine is an example of convergent evolution among different species. [202] [203] [204] Some people have reported increased hair fall and thinning after using Alpecin products. A possible cause of this is the presence of synthetic preservatives. These include propylparaben, methylparaben, sodium citrate, and sodium chloride. Koot P, Deurenberg P (1995). "Comparison of changes in energy expenditure and body temperatures after caffeine consumption". Annals of Nutrition & Metabolism. 39 (3): 135–42. doi: 10.1159/000177854. PMID 7486839.
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