Galpharm Treathay Hayfever Relief Fexofenadine, 30 Count (Pack of 1)

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If you remember more than 4 hours after, do not give the missed dose. Instead, wait until the next dose and carry on as normal. Human histamine wheal and flare studies following single and twice daily doses of fexofenadine hydrochloride demonstrate that the medicinal products exhibits an antihistaminic effect beginning within one hour, achieving maximum at 6 hours and lasting 24 hours. There is no evidence of tolerance to these effects after 28 days of dosing. A positive dose-response relationship between doses of 10 mg to 130 mg taken orally was found to exist. In this model of antihistaminic activity, it was found that doses of at least 130 mg were required to achieve a consistent effect that was maintained over a 24 hour period. Maximum inhibition in skin wheal and flare areas was greater than 80%. Clinical studies conducted in seasonal allergic rhinitis have shown that a dose of 120 mg is sufficient for 24 hour efficacy. EASY TO USE and drop free mist that you spray onto closed eyes and blink to apply the protective eye mist It is used for the relief of symptoms associated with seasonal and perennial allergic rhinitis and chronic idiopathic urticaria. You may need to take fexofenadine for longer if you're taking it to prevent symptoms, for example to stop hay fever symptoms when the pollen count is high.

If any of these apply to you, or if you are not sure, tell your doctor or pharmacist before taking this medicine. Try to take fexofenadine tablets at about the same time every day. Choose a time that is easy to remember. In adults, the following undesirable effects have been reported in post-marketing surveillance. The frequency with which they occur is not known (can not be estimated from available data) The recommended dose of fexofenadine hydrochloride for adults is 120 mg once daily taken before a meal.Fexofenadine does not undergo hepatic biotransformation and therefore will not interact with other medicinal products through hepatic mechanisms. Fexofenadine is a P-glycoprotein (P-gp) and organic-anion-transporting polypeptide (OATP) substrate. Concomitant use of fexofenadine with P-gp inhibitors or inducers can affect the exposure to fexofenadine. Coadministration of fexofenadine hydrochloride with P-gp inhibitors erythromycin or ketoconazole has been found to result in a 2-3 times increase in the level of fexofenadine in plasma. The changes were not accompanied by any effects on the QT interval and were not associated with any increase in adverse reactions compared to the medicinal products given singly.

Moderate] GENERALLY AVOID: Coadministration with large amounts of certain fruit juices, including grapefruit, orange and apple, may decrease the oral bioavailability of fexofenadine.Each film-coated tablet contains 120 mg of fexofenadine hydrochloride, which is equivalent to 112 mg of fexofenadine. Limited animal studies do not indicate direct or indirect harmful effects with respect to effects on pregnancy, embryonal/foetal development, parturition or postnatal development (see section 5.3). TREATHAY 120 mg tablets should not be used during pregnancy unless on the advice of a doctor. TREATHAY 120 mg tablets should not be used in children under 12 years of age. In children from 6 to 11 years of age: fexofenadine hydrochloride 30 mg tablet (prescription only medicine) is the appropriate formulation for administration and dosing in this population. Fexofenadine hydrochloride is rapidly absorbed into the body following oral administration, with T max occurring at approximately 1-3 hours post dose. The mean C max value was approximately 427 ng/ml following the administration of a 120 mg dose once daily.