Ovelle Cetomacrogol Cream BP (Formula A)

Product Information

Patient safety alert issued December 2014 on risk of death or serious harm from accidental ingestion of potassium permanganate preparations. Emollients help soften, moisturise and protect the skin. They play a central role in the treatment and management of dry skin conditions. For maximum effect, they should be applied regularly and as often as needed.

EMA is recommending that patients stop using Picato (ingenol mebutate), a gel for treating the skin condition actinic keratosis, while it continues its review of the medicine’s safety. NHSE commissioned drug for Paediatric indications (in line with NICE TA 455) - see Specialised Commissioning: Key documents

Pan Mersey APC (2022): ABROCITINIB tablets(Cibinqo®▼), TRALOKINUMAB injection (Adtralza®▼) or UPADACITINIB prolonged-release tablets(Rinvoq®▼) for treating moderate to severe atopic dermatitis Drugs carrying the NHS England logo are commissioned by them. Links to key documents, national programmes of care, and clinical reference groups are found below. Second line – broad- or narrow-band UVB light and psoralen plus UVA light (PUVA) and systemic non-biologics e.g. ciclosporin, methotrexate or acitretin

Third line – systemic biologics; Anti-TNFs – adalimumab, etanercept and infliximab and mono-clonal antibody ustekinumab which targets IL-12 and IL-23. A policy detailing clinician responsibilities in Shared Care Agreements must be referred to in all cases of Shared Care. Thermal burns from paraffin-containing ointments on clothing or bedding can be dangerous and can occur if ignited by cigarettes or naked flames. Slips and falls

Pharmacy product

Preparations containing an antibacterial (section 13.10) should be avoided unless infection is present or is a frequent complication. Humectant agents are hydrophilic (‘water-loving’), therefore attract and retain water in the stratum corneum, similar to the natural hydrating factors found in corneocytes. They include:

NHS England commissioned for paediatrics (aged 12-17); must be treated within a specialised treatment centre and meet the criteria within NICE TA534 for adults. Danby SG, Chalmers J, Brown K, Williams HC, Cork MJ. A functional mechanistic study of the effect of emollients on the structure and function of the skin barrier. Br J Dermatol 2016; 175: 1011–9. DOI: 10.1111/bjd.14684. Journal Non-formulary drugs - any drug or formulation not listed in the formulary is deemed to be non-formulary. Creams are more occlusive again. They include sorbolene cream, cetomacrogol cream, fatty cream, oily cream.

For the initial management of acne follow the local antibiotic guideline which can be found within Chapter 5. NICE TA814 (2022): Abrocitinib, tralokinumab or upadacitinib for treating moderate to severe atopic dermatitis Very dry skin may benefit from a greasy, occlusive moisturiser applied every couple of hours, while slightly dry skin may only need a light moisturiser at night. Glycopyrrolate solution iontophoresis can be offered to those who do not respond to tap water iontophoresis SC1 Requires specialist assessment to enable patient selection and also initiation, stabilisation and review of treatment and the patient`s condition.

May be prescribed in primary care for patients who cannot tolerate Anhydrol Forte ® despite use of emollients and topical steroids to minimise irritation. NICE TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people Occlusive agents provide a hydrophobic ( lipophilic) layer of oil on the surface of the skin, forming a protective barrier to reduce evaporative water loss from the stratum corneum (the outermost layer of the epidermis).

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For further information on the Atopic eczema in children: Management of atopic eczema in children from birth up to the age of 12years consult NICE CG 57 For the field treatment of nonhyperkeratotic, non-hypertrophic actinic keratosis (Olsen grade 1) of the face or scalp.