Niacyna B3 w leczeniu

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Lenz, Christoph (2021), "The climate disgrace of Visp", European Press Prize , retrieved 8 September 2023

Rubic T, Trottmann M, Lorenz RL (February 2004). "Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin". Biochemical Pharmacology. 67 (3): 411–9. doi: 10.1016/j.bcp.2003.09.014. PMID 15037193. There’s research to suggest that niacin could help protect those cells and possibly even lower the risk of type 1 diabetes in children who have a higher chance of developing this condition ( 10). Landray MJ, Haynes R, Hopewell JC, Parish S, Aung T, etal. (July 2014). "Effects of extended-release niacin with laropiprant in high-risk patients". N. Engl. J. Med. 371 (3): 203–12. doi: 10.1056/NEJMoa1300955. PMID 25014686. S2CID 23548060. Archived from the original on 29 June 2020 . Retrieved 27 June 2020. Bertram G. B.G. Katzung Bertram G. B.G., Basic and clinical pharmacology, New York: McGraw-Hill Medical Publishing Division, 2006, ISBN 0-07-145153-6 . brak strony (książka) Chromium. Taking niacin with chromium might lower your blood sugar. If you have diabetes and take niacin and chromium, closely monitor your blood sugar levels.

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This may translate to a decrease in heart disease risk, although several studies have found no link between niacin supplementation and a decrease in heart disease risk or deaths ( 4, 5). a b Health Canada (20 July 2005). "Dietary Reference Intakes". Government of Canada. Archived from the original on 14 June 2018 . Retrieved 20 June 2018. Vegetarian and vegan diets can provide adequate amounts if products such as nutritional yeast, peanuts, peanut butter, tahini, brown rice, mushrooms, avocado and sunflower seeds are included. Fortified foods and dietary supplements can also be consumed to ensure adequate intake. [5] [40] Food preparation [ edit ] For treating deficiency, the World Health Organization (WHO) recommends administering niacinamide i.e., nicotinamide, instead of niacin, to avoid the flushing side effect commonly caused by the latter. Guidelines suggest using 300mg/day for three to four weeks. [10] Dementia and dermatitis show improvement within a week. Because deficiencies of other B-vitamins may be present, the WHO recommends a multi-vitamin in addition to the niacinamide. [10] Niacin and Nicotinic Acid". Journal of the American Medical Association. 118 (10): 823. 7 March 1942. doi: 10.1001/jama.1942.02830100053014.

The high doses of niacin used to treat hyperlipidemia have been shown to elevate fasting blood glucose in people with type 2 diabetes. [16] Long-term niacin therapy was also associated with an increase in the risk of new-onset type 2 diabetes. [16] [17] Other adverse effects [ edit ] The U.S. Institute of Medicine (renamed National Academy of Medicine in 2015) updated Estimated Average Requirements (EARs) and Recommended Dietary Allowances (RDAs) for niacin in 1998, also Tolerable upper intake levels (ULs). In lieu of an RDA, Adequate Intakes (AIs) are identified for populations for which there is not sufficient evidence to identify a dietary intake level that is sufficient to meet the nutrient requirements of most people. [31] (see table). Ishii N, Nishihara Y (March 1981). "Pellagra among chronic alcoholics: clinical and pathological study of 20 necropsy cases". Journal of Neurology, Neurosurgery, and Psychiatry. 44 (3): 209–15. doi: 10.1136/jnnp.44.3.209. PMC 490893. PMID 7229643. Kraut A. "Dr. Joseph Goldberger and the War on Pellagra | Ashes on the Potomac". history.nih.gov. Archived from the original on 9 May 2020 . Retrieved 20 February 2017. Kirkland JB (May 2012). "Niacin requirements for genomic stability". Mutation Research. 733 (1–2): 14–20. doi: 10.1016/j.mrfmmm.2011.11.008. PMID 22138132. Archived from the original on 4 August 2020 . Retrieved 3 July 2019.Abe N, Ichimura H, Kataoka T, Morishita S, Shimizu S, Shoji T, Watanabe N (2007). "Pyridine and Pyridine Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi: 10.1002/14356007.a22_399. Pitsavas S, Andreou C, Bascialla F, Bozikas VP, Karavatos A (March 2004). "Pellagra encephalopathy following B-complex vitamin treatment without niacin". International Journal of Psychiatry in Medicine. 34 (1): 91–5. doi: 10.2190/29XV-1GG1-U17K-RGJH. PMID 15242145. S2CID 29070525. Archived from the original on 10 July 2012 . Retrieved 27 November 2009.

Cholesterol Medications". American Heart Association. 10 November 2018. Archived from the original on 5 April 2020 . Retrieved 8 May 2020. Niacin. Micromedex 2.0 Healthcare Series. http://www.micromedexsolutions.com. Accessed Aug. 9, 2017. Both the DRI and DRV describe amounts needed as niacin equivalents (NE), calculated as 1mg NE = 1mg niacin or 60mg of the essential amino acid tryptophan. This is because the amino acid is utilized to synthesize the vitamin. [4] [21] Your brain needs niacin — as a part of the coenzymes NAD and NADP — to get energy and function properly.a b LaRosa CJ (January 2020). "Hartnup Disease". Archived from the original on 8 July 2020 . Retrieved 6 July 2020. a b Nicotinic acid, [w:] PubChem [online], United States National Library of Medicine, CID: 938 ( ang.). Szczególnie narażone na niedostateczną podaż niacyny mogą być osoby niedożywione, osoby starsze, nadużywające alkoholu, z zaburzeniami wchłaniania jelitowego, z zaburzeniami wchłaniania tryptofanu, czy osoby nadużywające cukru.

a b CRC Handbook of Chemistry and Physics, David R. D.R. Lide (red.), wyd. 88, Boca Raton: CRC Press, 2007, s. 3-450, ISBN 978-0-8493-0488-0 ( ang.). Flavonoids (incl. 7,8-DHF, 8-prenylnaringenin, apigenin, baicalein, baicalin, biochanin A, calycosin, catechin, daidzein, daidzin, ECG, EGCG, epicatechin, equol, formononetin, glabrene, glabridin, genistein, genistin, glycitein, kaempferol, liquiritigenin, mirificin, myricetin, naringenin, penduletin, pinocembrin, prunetin, puerarin, quercetin, tectoridin, tectorigenin)Carpenter found in 1951, that niacin in corn is biologically unavailable, and can be released only in very alkaline lime water of pH 11. This explains why a Latin-American culture that used alkali-treated cornmeal to make tortilla was not at risk for niacin deficiency. [110] a b c "Nutrient reference values for Australia and New Zealand" (PDF). National Health and Medical Research Council. 9 September 2005. Archived from the original (PDF) on 21 January 2017 . Retrieved 19 June 2018. Kluczową rolą niacyny w naszym organizmie jest synteza koenzymów dinukleotydu nikotynamidoadeninowego (NAD) i fosforanu dinukleotydu nikotynamidoadeninowego (NADP), które biorą udział w ponad 400 reakcjach biochemicznych w organizmie i to głównie związanych z pozyskiwaniem energii z jedzenia, które spożywamy. Reiche I, Westphal S, Martens-Lobenhoffer J, Tröger U, Luley C, Bode-Böger SM (January 2011). "Pharmacokinetics and dose recommendations of Niaspan in chronic kidney disease and dialysis patients". Nephrology, Dialysis, Transplantation. 26 (1): 276–82. doi: 10.1093/ndt/gfq344. PMID 20562093.