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MAX Absorption Biotin Liquid Drops, 10000mcg of Biotin Per Serving, 60 Serving, No Artificial Preservatives, Vegan Friendly, Supports Hair Growth, Strong Nails and Glowing Skin, Made in USA

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In 1936, Fritz Kögl and Benno Tönnis documented isolating a yeast growth factor in a journal article titled " Darstellung von krystallisiertem biotin aus eigelb." (Representation of crystallized biotin from egg yolk). [43] The name biotin derives from the Greek word bios ('to live') and the suffix "-in" (a general chemical suffix used in organic chemistry). [5] Other research groups, working independently, had isolated the same compound under different names. Hungarian scientist Paul Gyorgy began investigating the factor responsible for egg-white injury in 1933 and in 1939, was successful identifying what he called "Vitamin H" (the H represents Haar und Haut, German for 'hair and skin'). [44] [45] Further chemical characterization of vitamin H revealed that it was water-soluble and present in high amounts in the liver. [46] After experiments performed with yeast and Rhizobium trifolii, West and Wilson isolated a compound they called co-enzyme R. [47] [48] By 1940, it was recognized that all three compounds were identical and were collectively given the name: biotin. [49] Gyorgy continued his work on biotin and in 1941 published a paper demonstrating that egg-white injury was caused by the binding of biotin by avidin. [50] [51] Unlike for many vitamins, there is insufficient information to establish a recommended dietary allowance, so dietary guidelines identify an "adequate intake" based on best available science with the understanding that at some later date this will be replaced by more exact information. [2] [9] [10] Wolf B (September 2016). "Biotinidase deficiency and our champagne legacy". Gene. 589 (2): 142–50. doi: 10.1016/j.gene.2015.10.010. PMID 26456103. Once absorbed, sodium-dependent multivitamin transporter (SMVT) mediates biotin uptake into the liver. [4] SMVT also binds pantothenic acid, so high intakes of either of these vitamins can interfere with transport of the other. [19] Metabolism and excretion [ edit ] Soleymani, T., Lo Sicco, K., & Shapiro, J. (2017). The infatuation with biotin supplementation: Is there truth behind its rising popularity? A comparative analysis of clinical efficacy versus social popularity. Journal of Drugs in Dermatology: JDD, 16 The amount of biotin you need each day depends on your age. Average daily recommended amounts are listed below in micrograms (mcg). Life Stage

West PM, Wilson PW (June 1939). "The Relation of "coenzyme R" to Biotin". Science. 89 (2322): 607–8. Bibcode: 1939Sci....89..607W. doi: 10.1126/science.89.2322.607. PMID 17751623. S2CID 30138816. a b "biotin | Origin and meaning of biotin by Online Etymology Dictionary". www.etymonline.com . Retrieved November 14, 2020. György, P (December 1939). "The Curative Factor (vitamin H) for Egg White Injury, with Particular Reference to Its Presence in Different Foodstuffs and in Yeast". Journal of Biological Chemistry. 131 (2): 733–44. doi: 10.1016/S0021-9258(18)73468-6. Bowen, R., et al. (2019). Best practices in mitigating the risk of biotin interference with laboratory testing.

In a different study, researchers found that children who experienced improved hair growth or quality after taking biotin supplements all had an underlying condition that caused a biotin deficiency ( 3). Morag E, Bayer EA, Wilchek M (December 1996). "Immobilized nitro-avidin and nitro-streptavidin as reusable affinity matrices for application in avidin-biotin technology". Anal Biochem. 243 (2): 257–263. doi: 10.1006/abio.1996.0514. PMID 8954558. However, high doses of biotin can interfere with lab tests by falsely skewing thyroid hormone levels, vitamin D levels, or other results, which could have a significant impact on your medical care ( 1, 13).

Biotin has also been used to treat the sypmptoms of multiple sclerosis (MS) and seborrhea (in babies). However, research has shown that biotin may not be effective in treating these conditions. Biotin produces neurotransmitters, which are essential for healthy brainfunction. Some studies have suggested that biotin supplementation has improved cognitive function in people with mild cognitive impairment. Helps with pregnancy That’s because many lab tests utilize biotin due to its ability to bind with specific proteins and detect certain health conditions ( 14). People who take certain classes of medications like antiepileptics and retinoids are also at risk of a biotin deficiency ( 9).http://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/legumes/art-20044278 Studies show that biotin supplements may help manage symptoms of diabetes. It might help reduce blood sugar levels, total cholesterol, and blood fats in some people with diabetes. But it doesn't have much effect on insulin levels. a b Laitinen OH, Hytönen VP, Nordlund HR, Kulomaa MS (December 2006). "Genetically engineered avidins and streptavidins". Cellular and Molecular Life Sciences. 63 (24): 2992–3017. doi: 10.1007/s00018-006-6288-z. PMID 17086379. S2CID 7180383.

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