Joined in 2023 
82 
63 About this deal
Niacinamide is used to treat acne and can help nourish and protect your skin, especially when it’s used with other products like retinol,” says Dr. Vij. “It’s a potent nutrient that rarely has side effects.” Chronic kidney disease is the progressive loss of kidney function that affects your body’s ability to clean and filter blood and control blood pressure. Another split-face study, this one published in 2011 in Dermatology Research and Practice, found that a topical 4% niacinamide treatment was effective for treating melasma over eight weeks in 27 participants. Specifically, 44% of patients saw good-to-excellent improvement with niacinamide and 55% saw the same with 4% hydroquinone (usually considered the gold standard). 10 So while the niacinamide was slightly less effective overall, it came with fewer side effects (present in 18% of participants) than the hydroquinone (present in 29%). What’s unique about this serum is that it can be used under the eyes. In fact, it’s encouraged because caffeine, wild indigo, and niacinamide brighten the appearance of dark circles while reducing puffiness. But don’t stop there. Cannabis and neuropeptide calm inflammation and boost hydration, so don’t skip out on the rest of your face.
Meet the experts: Purvisha Patel, M.D., board-certified dermatologist and founder of Visha Skincare; Elyse Love M.D., a board-certified dermatologist based in New York City; and Annie Gonzalez, M.D., board-certified dermatologist at Riverchase Dermatology in Miami. International Journal of Dermatology, Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris Since it’s water-soluble, your body doesn’t store this vitamin, which is why you need to eat nicotinic acid or niacinamide daily.
Some supplements that contain vitamin B3 only list niacin, but most supplements specify the form of niacin as either nicotinic acid or niacinamide. That said, it’s best practice to consult with your healthcare provider before supplementing with niacinamide — or any supplement for that matter — to assess your individual risk. Summary Dr. Patel also adds that the ingredient has a significant brightening benefit, “as it affects melanocytes, cells that play a role in pigment formation in the skin.” For that reason, you’ll find it in products designed to fight discoloration and lessen acne scars. What’s more, because niacinamide reduces irritation, “it can temper the effects of other anti-aging ingredients that can cause the skin to act up, like wrinkle-smoothing retinol or exfoliating alpha hydroxy acids,” Dr. Patel adds. When it comes to pigmentation issues, acne scars, and melasma, niacinamide’s lightening effects work better with other like-minded ingredients. Niacinamide and kojic acid, arbutin, or soy, helps clear discoloration faster. By working directly with labs, Good Molecules offers products that target skin issues like acne, redness, and hyperpigmentation without the traditional retail markup — much like The Ordinary. Powered by 10% niacinamide, glycerin, and betaine, this lightweight, water-based serum helps refine skin tone and texture for a brighter, healthier-looking complexion. Best Niacinamide Serum: The Bottom Line
Vitamin B3, in the form of nicotinic acid or niacinamide, is available as a supplement either by itself or alongside other vitamins and minerals in doses ranging from 14 to 1,000 mg per serving. We applied it after cleansing and before our usual moisturiser twice a week and are pleased to report that it didn’t result in any irritation – just smoother, brighter skin. If your two main areas of concern are ageing and congestion, then this serum is a must-have. Niacinamide is found in many foods, including meat, fish, eggs, green vegetables, beans and cereal grains, so getting enough dietary niacinamide should be easy if you follow a well-balanced diet. It’s also found in B complex supplements along with other vitamins. While promising, more research is needed before niacinamide supplements can be recommended as an intervention for type 1 diabetes. Summary However, the conversion of tryptophan to vitamin B3 is inefficient, as it takes 60 mg of tryptophan to make just 1 mg of vitamin B3 ( 1).As if that wasn't enough, niacinamide is also anti-inflammatory, great for those with acne , and can help combat hyperpigmentation and even help smooth lines and wrinkles . We love that it’s gentle enough for those with sensitive skin, making it a versatile staple in your beauty cabinet. Nothing has been proven to reduce the actual size of your pores. But niacinamide may help minimize their appearance by helping keep your skin smooth and clear. It also may help regulate the amount of oil your glands produce, which can prevent breakouts and clogged pores. 4. Possibly protect against skin cancer
Studies revealed that using a 5% concentration of niacinamide for 12 weeks showed a significant improvement in fine lines, wrinkles, red blotches, sallowness (yellowing), and elasticity. Additionally, niacinamide can begin to fade hyperpigmentation in as little as four weeks. With regular use, results can improve. Numerous studies came to the same conclusion, so the only thing left to do is try niacinamide for yourself. Niacinamide reduces environmental damage due to its ability to improve the skin’s barrier (its first line of defense) while also helping repair signs of past wear. Niacinamide benefits include enhanced resiliency, hydration, improved texture, reduced pore size, protection against free radicals, reduced inflammation, and the ability to fade discoloration and sunspots.
Regulates oil. The benefits of moisture retention aren’t just for those with dry skin types. Niacinimide can also help regulate the amount of oil the sebaceous glands produce and prevent your glands from going into overdrive. When used in conjunction with common moisturizing ingredients, like glycerin and hyaluronic acid, it can boost the product’s hydrating ability,” says Dr. Gonzalez. It has also been suggested that nicotinamide may increase insulin resistance, a hallmark of type 2 diabetes, but the evidence has been inconsistent ( 1, 28). Another great feature about niacinamide is that it pairs seamlessly with most other skincare ingredients (more on that in a bit). When shopping for the best niacinamide serum, be sure to read the label before committing to a product. You should always see niacinamide, no “nicotinic acid.” Even though the latter transforms into niacinamide, it can cause excessive redness and flushing . F or a niacinamide serum to be effective, look for a formula with a percentage of 2-10%. British Journal of Dermatology, Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier
Cutis, Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review Treats hyperpigmentation. Some research has found 5 percent niacinamide concentrations can be helpful in lightening dark spots. Benefits were seen after four weeks, but not beyond two months. This benefit may be due to increased collagen production.
Find in store
Protects against oxidative stress. Niacinamide helps build cells in the skin while also protecting them from environmental stresses, such as sunlight, pollution, and toxins.
Great Deal 
New Comment