Denamarin for Medium Dogs Tablet 225 mg, Pack of 30 Tablets

Product Information

Denamarin comes in tablet form to be given orally. These tablets must be given whole (don’t split them or crumble them up) because they are enteric-coated, to prevent them from being oxidized. Note: These are general guidelines. Always consult with a veterinarian for the correct dosage for your dog. Uses of Dexamethasone in Dogs

Dexamethasone is significantly more potent than prednisone. It has a more powerful anti-inflammatory effect, meaning a smaller dose is required to achieve similar effects. The choice between these steroids depends on the specific condition being treated and the dog’s overall health. 18. Are there specific tests required before starting a dog on dexamethasone? Denamarin Tablets are a nutritional supplement containing the antioxidant Silybin used to improve your pet’s liver function by increasing liver glutathione levels. Administering SAMe (S-Adenosylmethionine), which is found in Denamarin, has been shown to markedly increase liver levels of glutathione, an important compound for liver health formed when SAMe is metabolized. The SAMe in Denamarin has also been shown to help protect liver cells from cell death and may help with cell repair and regeneration. Denamarin also helps support your pet’s liver through administering silybin. Silybin is an active part of an extract from milk thistle, known as silymarin, and has been shown to support liver function by helping maintain a healthy oxidative balance. The tablets come in three different strengths: for cats and small dogs, for medium dogs, or for large dogs. Denamarin provides multi-faceted high level nutritional support for the liver due to its synergistic combination of S-adenosylmethionine (SAMe) and silybin. SAMe (S-Adenosylmethionine), which is found in Denamarin, has been shown to markedly increase liver levels of glutathione, S-Adenosylmethionine 172 mg and Silybin-phosphatidylcholine complex (SPC) 123 mg, providing 35 mg of Silybin A+BDenamarin helps to support the liver which is one of the largest organs in the body. How does it work? Signs of overdose may include excessive thirst, increased urination, extreme hunger, and potential behavioral changes. In severe cases, it can lead to more serious symptoms. If you suspect an overdose, seek veterinary attention immediately. 12. Can dexamethasone be used in pregnant or nursing dogs? When your pet’s liver is not working as effectively as normal, the production of S-adenosylmethionine (SAMe) decreases, which has further negative impacts on liver function. So Denamarin helps to supplement your pet with SAMe which has also in turn been shown to increase levels of the important antioxidant glutathione. Glutathione is a potent antioxidant that protects hepatic cells from toxins and death. Silybin High-Quality Ingredients: The Silybin found in Denamarin has shown better absorption by dogs than the standardized milk thistle extract found in many other products SAMe in a stabilized form to help with brain health and act as a neuroprotector. Denamarin also provides a bioavailable form of

Denamarin for Cats and Small Dogs tablets are ideal for cats because of their small size. If the pet is to receive more than one tablet daily, the Termination Notice. Walmart Inc. (“Walmart”) and Agropec Trading, LLC d/b/a Allivet ("Allivet") have terminated their agreement whereby Allivet Pet Pharmacy provided your pet pharmacy services. WalmartPetRx.com will continue to be operated by Allivet Pet Pharmacy solely in accordance with the dates below.

What special precautions are there:

Because the tablet must be kept intact to prevent destruction by moisture, administration range is based on the nearest whole-tablet. The chart below is provided as a guide for administration. Continuity of Care & Billing Statement Information. Allivet Pet Pharmacy will continue to fill your prescriptions and provide your AutoShip products, unless you otherwise notify Allivet Pet Pharmacy that you would like to transfer your pet’s prescription(s) to another pharmacy in accordance with Section 5 below. Following 9/1/2023, the billing information on your credit statement will change to reflect a charge from Allivet Pet Pharmacy instead of Walmart Pet Rx. Denamarin combines a pure S-Adenosylmethionine (SAMe) with silybin to provide a one-two punch to keep your pets liver healthy. Silybin supports the flow of bile through the liver which helps with the digestion and absorption of nutrients from your pet's diet. Silybin also helps to regenerate liver cells and may enhance levels of glutathione, an antioxidant that helps to protect cells from toxins such as free radicals. Brand Name:

administering tablets to their pets, Denamarin tablet(s) may be disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach However, Deanamarin is also showing promise in other fields of medicine. It is thought that SAMe supplementation can help in the management of canine cognitive dysfunction and osteoarthritis (joint pain). A study in humans showed promising results for the treatment of osteoarthritisbut further studies are needed in this area. Pharmacy of Choice. You have the right to choose your pharmacy provider. If you would like to have your existing prescription transferred to another pharmacy, and Allivet Pet Pharmacy receives your consent to do so, your prescription will be transferred to such pharmacy in accordance with Allivet Pet Pharmacy’s standard procedures and applicable law. In a pharmacokinetic study with fasted dogs given S-Adenosylmethionine, peak plasma levels were recorded in most dogs within 4 hours of administration. 1 A pharmacokinetic study in fasted cats showed peak plasma levels at 2-4hours post S-Adenosylmethionine administration. 3,31 Results from a clinical trial indicate that Denamarin acts as a hepatoprotectant in dogs undergoing chemotherapy with lomustine (CCNU). 30 Pharmacokinetics

Denamarin combines pure S-Adenosylmethionine (SAMe) with Silybin to provide a one-two punch to keep your pets liver healthy. Silybin supports the flow of bile through the liver which helps with the digestion and absorption of nutrients from your pet's diet. Silybin also helps to regenerate liver cells and may enhance levels of glutathione, an antioxidant that helps to protect cells from toxins such as free radicals. It comes in a pork liver flavored chewable tablet that most dogs love. Cautions: For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulty In addition to supporting liver health, Denamarin may also support brain health as S-Adenosylmethionine has been shown to function as a neuroprotective agent. 4,18,19 The ingredients in Denamarin ® possess exceptionally wide margins of safety. Oral acute toxicity studies in rats indicated an LD 50 greater than 4,650 mg/kg for S-Adenosylmethionine. 2 Clinically healthy dogs administered 20 mg/kg/day of S-Adenosylmethionine for 6 weeks and clinically healthy cats administered S-Adenosylmethionine at 2 times the recommended daily amount for 113 days remained healthy with no adverse effects from the administration. 1,3