TA-BEX ANTI-SMOKING TABLETS - SOP-HARMA UK TM

Product Information

At ‘Tabex Cytisine’ we aim to provide our customers with a safe, natural and successful way to help give up smoking. We are confident you will love the positive health benefits of Tabex by Sopharma. Taken together with the results from earlier studies these findings support the argument for a drug evaluation programme undertaken to modern standards. This would include large scale clinical trials of this drug to a standard that would be acceptable by regulatory authorities around the world. More information is also required on the pharmacokinetic properties of the drug, its safety profile and ideally studies varying the dose and the duration of dose. The obvious advantage of this medication is its cost. It offers the prospect of providing access to effective treatment to help with smoking cessation to millions of smokers who would not otherwise be able to afford it. For healthcare providers it offers the prospect of hugely reduced costs. A trial by Monova et al is described in a review of evidence produced by the manufacturers of Tabex, 23 but it remains unpublished. At 4-week follow-up, cytisine was significantly more effective than placebo (Monova et al, unpublished report TAB-SPH-04014: Sopharma plc, 2004). Success Stories with Tabex: Real People, Real Results | See how others have successfully quit smoking with the help of Tabex Cytisine is a compound derived from the plant, cytisus laburnum. It is a nicotinic partial agonist binding with high affinity to a number of different subtypes of the neuronal nicotinic receptors, including receptors composed of α 4 and β 2 subunits 13 , 14 which are believed to be central to the effect of nicotine on the reward pathway. 4 Because it has a high affinity for the receptor, cytisine prevents other ligands such as nicotine from attaching to it. However, once attached to the receptor, its effect is much less than that of nicotine. As a result, the drug would be expected to reduce the rewarding effects of nicotine and to decrease craving and attenuate nicotine withdrawal symptoms, but not be addictive itself or provide positive reward. Despite its properties there is no dissemination of the drug in western countries. However, cytisine has provided the starting point for a new medication for smoking cessation, varenicline, that has recently undergone clinical trials. 4

If doctors are suddenly able to prescribe cytisine, patients would not be able to buy it because nobody in the UK currently produces or supplies enough. But his can’t be right. If no company would be willing to produce it although it had been licensed, I’m pretty sure a company already producing it in Eastern Europe would be delighted to scale up their operation. (Refusal of a UK drug company to produce a licensed drug would also show that the patent system is not just a reward for research and development but a warrant to overcharge — that’s another point). Each Tabex tablet contains 1.5 mg of cytisine. Quitters should take 6 tablets a day for the first three days after they quit smoking, and then reduce this to 2 tablets a day until day 25, the last day of treatment. The 12‐month success rate was similar to the figure observed in the evaluation of the UK smoking cessation services. This was despite the fact that the smokers were more dependent on average, as indicated by the FTND, and most only attended one session of psychological support. The observation that cytisine satisfies smokers led to the development of cytisine tablets as a treatment for smokers wishing to quit. The tablets have been produced in Bulgaria with the trade name Tabex since 1964. 1 During the 1970s Tabex was used in several other Eastern European countries and it remains in use in Bulgaria and Poland. The tablets were originally produced by Pharmachim and later by Sopharma, another Bulgarian pharmaceutical company ( http://www.sopharma.com/tabex.phtml). Summarising the results of drug trials faces a risk of publication bias—that is, negative results are not published. 32 The risk is reduced in this case by the fact that the drug manufacturer funded only one of the nine trials, but possible under-reporting of negative results cannot be ruled out in any meta-analysis.How to use Tabex to quit smoking in 25 days. Tabex is administered orally. At the end of the third day you will take your last cigarette.

Tabex is a natural herbal product containing Cytisine which is from the Laburnum tree which grows wildly in hot climates particularly in Bulgaria. It has been used Worldwide for over 40 years to help with the cravings of smoking. It is a natural herbal product available over the counter without a prescription. Tabex® is the safest and most tolerable anti-smoking product on the world market and has helped millions worldwide to stop smoking. Tabex tablets do not contain Nicotine, it is totally safe and natural without any reported side effects. Buy Tabex and quit smoking today! Tabex UK and Worldwide! The course of treatment usually lasts 25-30 days. This course can be cycled twice and has shown to be more effective. It could just be inertia — the Department of Health may not be used to doing these kinds of things. This is no excuse because millions are being wasted and smokers need help quitting. It’s time for someone in the Department of Health to follow my colleague’s advice to transcend the “ Alice in Wonderland world of regulation” to find a way let doctors prescribe cytisine. Until that happens I’ll have to suffer through my brother in law’s conspiracy lectures. Cytisine may be cheap way to help people quit quit smoking but it doesn’t stop them from buying into conspiracy theories. Tabex® contains the known plant extract Cytisine. Tabex has been available in Eastern Europe for over 50 years.But what about its effectiveness? Can it compete with nicotine replacement therapy or other prescription medications? The answer is yes! Studies have shown that Tabex has comparable effectiveness to other smoking cessation medications at a fraction of the cost.