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Despite the extremely rapid development of effective mRNA and viral vector vaccines, worldwide vaccine equity has not been achieved. The development and use of whole inactivated virus (WIV) and protein-based vaccines have also been recommended, especially for use in developing countries. [213] [214] a b c d e Li C, Zhao C, Bao J, Tang B, Wang Y, Gu B (November 2020). "Laboratory diagnosis of coronavirus disease-2019 (COVID-19)". Clinica Chimica Acta; International Journal of Clinical Chemistry. 510: 35–46. doi: 10.1016/j.cca.2020.06.045. PMC 7329657. PMID 32621814.

Coronavirus (COVID-19) in the UK Something went wrong - Coronavirus (COVID-19) in the UK

Scientific Brief: SARS-CoV-2 Transmission". Centers for Disease Control and Prevention. 7 May 2021 . Retrieved 8 May 2021. Fungal infections such as aspergillosis, candidiasis, cryptococcosis and mucormycosis have been recorded in patients recovering from COVID‑19. [75] [76] Cause The use of passive antibodies to treat people with active COVID‑19 is also being studied. This involves the production of convalescent serum, which consists of the liquid portion of the blood from people who recovered from the infection and contains antibodies specific to this virus, which is then administered to active patients. [514] This strategy was tried for SARS with inconclusive results. [514] An updated Cochrane review in May 2021 found high certainty evidence that, for the treatment of people with moderate to severe COVID‑19, convalescent plasma did not reduce mortality or bring about symptom improvement. [515] There continues to be uncertainty about the safety of convalescent plasma administration to people with COVID‑19 and differing outcomes measured in different studies limits their use in determining efficacy. [515] Bioethics Jiang S, Xia S, Ying T, Lu L (May 2020). "A novel coronavirus (2019-nCoV) causing pneumonia-associated respiratory syndrome". Cellular & Molecular Immunology. 17 (5): 554. doi: 10.1038/s41423-020-0372-4. PMC 7091741. PMID 32024976.

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US Ambassador to Indonesia Sung Kim accompanied by local officials at the Presidential Palace wearing face masks amid the COVID-19 pandemic Additionally, people with COVID‑19 and acute respiratory distress syndrome (ARDS) have classical serum biomarkers of CRS, including elevated C-reactive protein (CRP), lactate dehydrogenase (LDH), D-dimer, and ferritin. [148]

Coronavirus cases, deaths, vaccinations by country Covid map: Coronavirus cases, deaths, vaccinations by country

Estimates of the risk of hospital admission for coronavirus (COVID-19) and death involving COVID-19 by vaccination status, overall and by age group, using anonymised linked data from Census 2021. Experimental Statistics. Neurologic manifestations include seizure, stroke, encephalitis, and Guillain–Barré syndrome (which includes loss of motor functions). [69] [70] Following the infection, children may develop paediatric multisystem inflammatory syndrome, which has symptoms similar to Kawasaki disease, which can be fatal. [71] [72] In very rare cases, acute encephalopathy can occur, and it can be considered in those who have been diagnosed with COVID‑19 and have an altered mental status. [73]Grant MC, Geoghegan L, Arbyn M, Mohammed Z, McGuinness L, Clarke EL, Wade RG (23 June 2020). "The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): A systematic review and meta-analysis of 148 studies from 9 countries". PLOS ONE. 15 (6): e0234765. Bibcode: 2020PLoSO..1534765G. doi: 10.1371/journal.pone.0234765. PMC 7310678. PMID 32574165. S2CID 220046286. During the early stages of the outbreak, the number of cases doubled approximately every seven and a half days. [437] In early and mid-January 2020, the virus spread to other Chinese provinces, helped by the Chinese New Year migration and Wuhan being a transport hub and major rail interchange. [99] On 20 January, China reported nearly 140 new cases in one day, including two people in Beijing and one in Shenzhen. [438] Later official data shows 6,174 people had already developed symptoms by then, [361] and more may have been infected. [439] A report in The Lancet on 24 January indicated human transmission, strongly recommended personal protective equipment for health workers, and said testing for the virus was essential due to its "pandemic potential". [135] [440] On 30 January, the WHO declared COVID-19 a Public Health Emergency of International Concern. [439] By this time, the outbreak spread by a factor of 100 to 200 times. [441] McNeil Jr DG (2 February 2020). "Wuhan Coronavirus Looks Increasingly Like a Pandemic, Experts Say". The New York Times. ISSN 0362-4331. Archived from the original on 2 February 2020 . Retrieved 4 April 2020. Baruah C, Devi P, Deka B, Sharma DK (June 2021). "Mucormycosis and Aspergillosis have been Linked to Covid-19-Related Fungal Infections in India". Advancements in Case Studies. 3 (1). doi: 10.31031/AICS.2021.03.000555. ISSN 2639-0531. S2CID 244678882– via ResearchGate.

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Romiti GF, Corica B, Lip GY, Proietti M (June 2021). "Prevalence and Impact of Atrial Fibrillation in Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis". Journal of Clinical Medicine. 10 (11): 2490. doi: 10.3390/jcm10112490. PMC 8200114. PMID 34199857. Coagulation: During pregnancy, there are higher levels of circulating coagulation factors, and the pathogenesis of SARS-CoV-2 infection can be implicated. The thromboembolic events with associated mortality are a risk for pregnant women. [159] a b Gandhi RT, Lynch JB, Del Rio C (October 2020). "Mild or Moderate Covid-19". The New England Journal of Medicine. 383 (18): 1757–1766. doi: 10.1056/NEJMcp2009249. PMID 32329974. Main article: COVID-19 drug repurposing research Seven possible drug targets in viral replication process and drugsa b "Naming the coronavirus disease (COVID-19) and the virus that causes it". World Health Organization (WHO). Archived from the original on 28 February 2020 . Retrieved 13 March 2020. Clinical Questions about COVID-19: Questions and Answers". Centers for Disease Control and Prevention. 4 March 2021. Biswas Riddhideep; Pal Anish; Pal Ritam; Sarkar Sourav; Mukhopadhyay Achintya (2022). "Risk assessment of COVID infection by respiratory droplets from cough for various ventilation scenarios inside an elevator: An OpenFOAM-based computational fluid dynamics analysis". Physics of Fluids. 34 (1): 013318. arXiv: 2109.12841. Bibcode: 2022PhFl...34a3318B. doi: 10.1063/5.0073694. PMC 8939552. PMID 35340680. S2CID 245828044.