Nikura Spearmint Essential Oil - 10ml | 100% Pure Natural Oils | Perfect for Hair Care, Spider Repellent, Energy Boost, Candle Making | Great for Self Care, Massage, Skin | Vegan & UK Made

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In the same year, Mugisha and colleagues tested the acute and subacute toxicities of the leaves of this plant in Swiss mice and Wistar albino rats, respectively [ 114]. For acute toxicity, animals received intragastrically over 72 hours, doses of 10000, 12000, 14000, 16000, and 18000 g/kg b.w of the 70% ethanolic extract. Therefore, a death rate of 100% was obtained at the highest dose with some signs of toxicity (convulsions, abdominal muscle contractions, and hyperurination) above 12000 mg/kg b.w. The LD 50 value was 13606 mg/kg b.w. Regarding subacute toxicity (28 days), ethanol leaf extract (500, 1000, and 1500 mg/kg b.w) caused no mortality or signs of toxicity. However, it significantly increased the levels of mean corpuscular hemoglobin concentration, lymphocytes, blood cells count, and aspartate transferase and significantly reduced haematocrit. At the same time, serum urea and creatinine levels were not affected, confirmed by histopathological data. A. Lamiri, S. Lhaloui, B. Benjilali, and M. Berrada, “Fumigant toxic activity of essential oils on Sitophilus granarius (linné),” Physical and Chemical News, vol. 1, 2001.View at: Google Scholar Lavender and orange essential oil blend is a powerful combination of two naturally beneficial oils. Whether you are looking to reduce stress and anxiety, promote relaxation, or uplift your mood, this essential oil blend can help. Repeat the inhalation process as desired. It's important to avoid excessive or prolonged inhalation, as this can potentially irritate the respiratory system. Be cautious with this combination• Medications that can harm the liver (Hepatotoxic drugs) interacts with SPEARMINT

Spearmint oil natural, Mentha spicata L. 8008-79-5 Spearmint oil natural, Mentha spicata L. 8008-79-5

The study conducted by Jabbar and Kathem [ 99] evaluated the preventive effect of ethanolic extract of leaves from M. spicata on irinotecan-induced mucositis in mice. The results revealed that the ethanolic extract of M. spicata markedly reduced jejunal tissue IL-1 β (3.47 ± 1.23 vs. 6.5 ± 0.36 ng/mL), and fecal β-glucuronidase activity (79.78 ± 10.7 vs. 120.6 ± 8.3 U) compared to no-treated mice. In addition, histological investigation of the jejunum section of the animal after administration of irinotecan and ethanolic extract of M. spicata showed enhancements in mucositis features. 3.5.6. Antidiabetic Activity Menthol has an aroma similar to peppermint. However, unlike in peppermint, spearmint leaves have a negligible menthol content. Spearmint oil can be used as a substitute for peppermint when it is unavailable and possesses similar medicinal properties due to the presence of similar compounds in its essential oil. Instances of its use in ancient Greece have even been found in historical records. Health Benefits of Spearmint Essential Oil Pregnancy: Spearmint and spearmint oil are commonly consumed in foods. But spearmint is possibly unsafe when taken by mouth in large amounts during pregnancy. Very large doses of spearmint tea might damage the uterus. Avoid using large amounts of spearmint during pregnancy. Hunt R, Dienemann J, Norton HJ, Hartley W, Hudgens A, Stern T, Divine G. Aromatherapy as treatment for postoperative nausea: a randomized trial. Anesth Analg 2013;117(3):597-604. View abstract.S. Kizil and Ö. Tonçer, “Influence of different harvest times on the yield and oil composition of spearmint (Mentha spicata L. var. spicata),” Journal of Food Agriculture and Environment, vol. 4, no. 3–4, pp. 135–137, 2006.View at: Google Scholar By respecting the chronology of the studies carried out over time, Ebrahimzadeh et al. [ 9] examined the antioxidant capacity of M. spicata aerial parts in vitro using eight assay systems. They recorded the best activity with the DPPH test (IC 50 = 105.8 ± 3.98 μg/mL), followed by the assay of nitric oxide-scavenging activity (IC 50 = 210.6 ± 7.7 μg/mL) and scavenging of H 2O 2 (IC 50 = 631.1 ± 26.0 μg/mL). In addition, good antioxidant activity has been demonstrated by Hussain et al. [ 5] (IC 50 = 13.3 ± 0.6 μL/mL) and by Liu et al. [ 11] (IC 50 = 72.07 ± 0.34 mg/mL), using DPPH free radical-scavenging ability. Moreover, the antioxidant power of M. spicata aerial parts has been tested by Benedec et al. [ 50] using only the DPPH radical scavenging assay, which showed a value of 18.34 ± 2.2% at the concentration of 0.4 mg/mL. A Tunisian research team also confirmed this when they recorded an important antiradical (IC 50 = 10 ± 0.24 μg/mL) and superoxide anion (IC 50 = 1.33 ± 0.10 μg/mL) scavenging ability [ 104]. Furthermore, according to Teixeira and collaborators, the essential oil of this plant was shown to be a potent antioxidant by exhibiting a dose-dependent antioxidant effect at the concentrations tested (25, 50, 100, 150, 200, 250, 300, and 500 μg/mL), determined by the sequestration of the DPPH radical and by the β-carotene-linoleic acid method [ 44]. To test the application for alone or combined, three essential oils were isolated from three medicinal plant species belonging to the Mentha genus to manage the rice weevil Sitophilus oryzae (Curculionidae). The study conducted by Haouel-Hamdi et al. [ 93] showed that binary combined Tunisian spearmint oils from M. rotundifolia, M. viridis, and M. longifolia leaves have exerted an important anti-insecticide activity against Sitophilus oryzae. However, Mentha essential oils alone revealed the lowest repellent activity to S. oryzae adults. After 24 days of exposure, LC 50 and LC 95 values of fumigant toxicity of M. viridis essential oils alone was 100.16 μL/L air and 192.197 μL/L air, respectively, against S. oryzae adults. In addition, the LT 50 value was 45.52 h for M. viridis, and the percentage of mortality was 22% at a concentration of 71.43 μL/L air. 3.5.5. Anti-Inflammatory Activity Safety Precautions: Made for ages 12 and up. Essential oil roll-ons come ready-made for applying to skin, diluted in organic fractionated coconut oil base.

Peppermint Oil: Uses, Benefits, and Side Effects - Healthline Peppermint Oil: Uses, Benefits, and Side Effects - Healthline

E. Sevi̇ndi̇k, Ç. Yamaner, C. Kurtoğlu, and B. Ti̇n, “Chemical composition of mentha spicata L. Subsp. tomentosa and M. Pulegium L., and their antimicrobial activity on strong pathogen microorganisms,” Notulae Scientia Biologicae, vol. 9, 2017.View at: Google Scholar Rafii, F. and Shahverdi, A. R. Comparison of essential oils from three plants for enhancement of antimicrobial activity of nitrofurantoin against enterobacteria. Chemotherapy 2007;53(1):21-25. View abstract. The antibacterial, antifungal, and antiviral properties of essential oil of spearmint make it a disinfectant. It can help get rid of both internal and external infections. It is particularly effective in protecting internal wounds and ulcers, like those in the stomach, food pipe, and intestines. In ancient Greece, it was used to treat infectious diseases like scabies, dermatitis, athlete’s foot, syphilis, gonorrhea, and other infectious or transmittable diseases. CarminativeFor testing the analgesic and antipyretic effects of methanol extract from M. spicata, Yousuf et al. [ 97] in their study demonstrated that the methanol extract from the whole plant of M. spicata had markedly increased the reaction time of mice in a dose-dependent manner by the hot-plate test ( ) proving its marked analgesic effect. In addition, using the acetic acid-induced writhing method, the methanol extract of M. spicata also exhibited a significant analgesic action. The inhibition at the dose of 500 mg/kg was estimated at 60.30%. On the other hand, using Brewer’s yeast-induced pyrexia in rats, the methanol extract of M. spicata was revealed to exert a strong marked ( ) antipyretic activity at the dose of 500 mg/kg at 3 h than at a dose of 100 mg/kg at 2 h. 3.5.10. Antihemolytic Activity H. Boukhebti, A. N. Chaker, H. Belhadj, F. Sahli, H. Laouer, and D. Harzallah, “Chemical composition and antibacterial activity of Mentha pulegium L. and Mentha spicata L. essential oils,” Der Pharmacia Lettre, vol. 3, no. 4, p. 10, 2011.View at: Google Scholar A. Chrysargyris, P. Xylia, G. Botsaris, and N. Tzortzakis, “Antioxidant and antibacterial activities, mineral and essential oil composition of spearmint (Mentha spicata L.) affected by the potassium levels,” Industrial Crops and Products, vol. 103, pp. 202–212, 2016.View at: Google Scholar