Niacyna B3 w leczeniu

Product Information

Niacyna - działanie, wskazania do suplementacji, dawkowanie. Jakie są sposoby na niedobory witaminy B3? Recommended Dietary Allowance (RDA): average daily level of intake that is enough to meet the nutrient requirements of nearly all (97% to 98%) healthy people. Prescription products can be immediate release (Niacor, 500mg tablets) or extended release (Niaspan, 500 and 1000mg tablets). Niaspan has a film coating that delays release of the niacin, resulting in an absorption over a period of 8–12 hours. This reduces vasodilation and flushing side effects, but increases the risk of hepatotoxicity compared to the immediate release drug. [89] [90]

Nutritional Yeast Flakes (two tablespoons = 16 grams". NutritionData.Self.com. Archived from the original on 11 April 2020 . Retrieved 13 May 2020. Carpenter KJ (1983). "The Relationship of Pellagra to Corn and the Low Availability of Niacin in Cereals". Nutritional Adequacy, Nutrient Availability and Needs. Experientia Supplementum. Vol.44. pp.197–222. doi: 10.1007/978-3-0348-6540-1_12. ISBN 978-3-0348-6542-5. PMID 6357846. Synthetic xenoestrogens (e.g., alkylphenols, bisphenols (e.g., BPA, BPF, BPS), DDT, parabens, PBBs, PHBA, phthalates, PCBs) Metaanaliza 11 kontrolowanych badań klinicznych przeprowadzona w 2009 roku wykazała, iż niacyna, użyta jako jedyny lek lub też w kombinacji z innymi lekami, znacznie zmniejszyła ilość głównych incydentow chorób wieńcowych (zawałów, udarów mózgu) oraz rozwój miażdżycy [30].This may translate to a decrease in heart disease risk, although several studies have found no link between niacin supplementation and a decrease in heart disease risk or deaths ( 4, 5). Drugs.com, Abbott Receives FDA Approval for Simcor (Niaspan / simvastatin), a Novel Combination Medicine for Comprehensive Cholesterol Management" (Press release) . Retrieved 15 March 2008.

Romani M, Hofer DC, Katsyuba E, Auwerx J (April 2019). "Niacin: an old lipid drug in a new NAD+ dress". J. Lipid Res. 60 (4): 741–6. doi: 10.1194/jlr.S092007. PMC 6446705. PMID 30782960.

a b c d e "Niaspan- niacin tablet, film coated, extended release". DailyMed. 20 August 2013. Archived from the original on 14 November 2022 . Retrieved 14 November 2022. Recommendations for niacin and other nutrients are provided in the Dietary Reference Intakes (DRIs), which are developed by the Food and Nutrition Board at the National Academies of Sciences, Engineering, and Medicine. DRI is the term for a set of reference values that are used to plan and assess the nutrient intakes of healthy people. These values, which vary by age and sex, include: Toth PP, Murthy AM, Sidhu MS, Boden WE (2015). "Is HPS2-THRIVE the death knell for niacin?". J Clin Lipidol. 9 (3): 343–50. doi: 10.1016/j.jacl.2015.01.008. PMID 26073392. Niacin content per 100 grams; select food subset, abridged list by food groups". United States Department of Agriculture, Agricultural Research Service, USDA Branded Food Products Database v.3.6.4.1. 17 January 2017. Archived from the original on 2 February 2017 . Retrieved 23 January 2017. Wan Z, Zheng J, Zhu Z, Sang L, Zhu J, Luo S, Zhao Y, Wang R, Zhang Y, Hao K, Chen L, Du J, Kan J, He H. Wan Z, et al. Front Nutr. 2022 Dec 13;9:1031502. doi: 10.3389/fnut.2022.1031502. eCollection 2022. Front Nutr. 2022. PMID: 36583209 Free PMC article. Review.

Stosowanie suplementów powinno być zindywidualizowane i zweryfikowane przez pracownika służby zdrowia, takiego jak zarejestrowany dietetyk, farmaceuta lub lekarz. Żaden suplement nie jest przeznaczony do leczenia lub zapobiegania chorobom. In the United States, prescription niacin, in immediate-release and slow-release forms, is used to treat primary hyperlipidemia and hypertriglyceridemia. [23] [24] It is used either as a monotherapy or in combination with other lipid-modifying drugs. Dosages start at 500mg/day and are often gradually increased to as high as 3000mg/day for immediate release or 2000mg/day for slow release (also referred to as sustained release) to achieve the targeted lipid changes (lower LDL-C and triglycerides, and higher HDL-C). [23] [24] Prescriptions in the US peaked in 2009, at 9.4 million [ citation needed] and had declined to 800 thousand by 2020. [18] W 1981 r. zaobserwowano, że codzienne przyjmowanie niacyny w dawce 3 × 1 g przez 5 tygodni doprowadziło do spadku poziomu cholesterolu o 22% [27]. Niacyna przyjmowana w celach terapeutycznych powinna być wprowadzana do ustroju stopniowo, aby zapobiec wystąpieniu niepożądanych działań. Weidel H (1873). "Zur Kenntniss des Nicotins". Justus Liebigs Annalen der Chemie und Pharmacie. 165 (2): 330–49. doi: 10.1002/jlac.18731650212. Archived from the original on 4 August 2020 . Retrieved 3 July 2019.

a b "Nutrient Recommendations: Dietary Reference Intakes (DRI)". National Institutes of Health, Office of Dietary Supplements. Archived from the original on 2 July 2020 . Retrieved 30 June 2020. Małe niedobory niacyny mogą powodować zwolnienie metabolizmu, przez co zmniejszenie tolerancji na zimno. a b c "USDA National Nutrient Database for Standard Reference Legacy: Niacin" (PDF). U.S. Department of Agriculture, Agricultural Research Service. 2018. Archived (PDF) from the original on 9 October 2022 . Retrieved 12 May 2020. Kirkland JB (May 2012). "Niacin requirements for genomic stability". Mutation Research. 733 (1–2): 14–20. doi: 10.1016/j.mrfmmm.2011.11.008. PMID 22138132. Archived from the original on 4 August 2020 . Retrieved 3 July 2019.