MyProtein Creatine Monohydrate,Powder - 1KG

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Deminice R, et al. Creatine supplementation prevents hyperhomocysteinemia, oxidative stress and cancer-induced cachexia progression in Walker-256 tumor-bearing rats. Amino Acids. 2016;48(8):2015–24. Burke DG, et al. Effect of creatine and weight training on muscle creatine and performance in vegetarians. Med Sci Sports Exerc. 2003;35(11):1946–55. Tarnopolsky MA. Potential benefits of creatine monohydrate supplementation in the elderly. Curr Opin Clin Nutr Metab Care. 2000;3(6):497–502. Lopez RM, et al. Does creatine supplementation hinder exercise heat tolerance or hydration status? a systematic review with meta-analyses. J Athl Train. 2009;44(2):215–23.

Devries MC, Phillips SM. Creatine supplementation during resistance training in older adults-a meta-analysis. Med Sci Sports Exerc. 2014;46(6):1194–203. Hausmann ON, et al. Protective effects of oral creatine supplementation on spinal cord injury in rats. Spinal Cord. 2002;40(9):449–56.Beard E, Braissant O. Synthesis and transport of creatine in the CNS: importance for cerebral functions. J Neurochem. 2010;115(2):297–313. Spillane M, et al. The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels. J Int Soc Sports Nutr. 2009;6:6. Creatine supplements also increase phosphocreatine stores in your brain, which may promote brain health and improve symptoms of neurological disease. Summary Gao J, et al. (2022). Creatine kinase and prognosis in amyotrophic lateral sclerosis: A literature review and multi-centre cohort analysis.

Paddon-Jones D, Borsheim E, Wolfe RR. Potential ergogenic effects of arginine and creatine supplementation. J Nutr. 2004;134(10 Suppl):2888S–94S. discussion 2895S.Rawson ES, Venezia AC. Use of creatine in the elderly and evidence for effects on cognitive function in young and old. Amino Acids. 2011;40(5):1349–62. Kreider RB, et al. ISSN exercise & sport nutrition review: research & recommendations. J Int Soc Sports Nutr. 2010;7:7. Andreassen OA, et al. Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation. J Neurochem. 2001;77(2):383–90. Creatine is one of the world’s most tested supplements and has an outstanding safety profile. Does creatine work for women? Tarnopolsky MA, MacLennan DP. Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females. Int J Sport Nutr Exerc Metab. 2000;10(4):452–63.

Food supplements are not intended to replace a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended usage. Keep out of reach of children.

Ellery SJ, et al. (2016). Creatine for women: A review of the relationship between creatine and the reproductive cycle and female-specific benefits of creatine therapy. Stone MH, et al. Effects of in-season (5 weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Int J Sport Nutr. 1999;9(2):146–65. Davani-Davari D, et al. (2018). Potential adverse effects of creatine supplement on the kidney in athletes and bodybuilders.

Kreider RB, et al. Long-term creatine supplementation does not significantly affect clinical markers of health in athletes. Mol Cell Biochem. 2003;244(1–2):95–104. A number of studies have investigated the short and long-term therapeutic benefit of creatine supplementation in children and adults with various neuromuscular diseases like muscular dystrophies [ 160, 161, 162, 163, 164, 165], Huntington’s disease [ 23, 166, 167, 168, 169, 170, 171]; Parkinson disease [ 23, 40, 166, 172, 173, 174]; mitochondria-related diseases [ 29, 175, 176, 177]; and, amyotrophic lateral sclerosis or Lou Gehrig’s Disease [ 166, 178, 179, 180, 181, 182, 183, 184]. These studies have provided some evidence that creatine supplementation may improve exercise capacity and/or clinical outcomes in these patient populations. However, Bender and colleagues [ 23] recently reported results of several large clinical trials evaluating the effects of creatine supplementation in patients with Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS). A total of 1,687 patients took an average of 9.5 g/day of creatine for a total of 5,480 patient years. Results revealed no clinical benefit on patient outcomes in patients with PD or ALS. However, there was some evidence that creatine supplementation slowed down progression of brain atrophy in patients with HD (although clinical markers were unaffected). Whether creatine supplementation may have a role in mediating other clinical markers in these patient populations and/or whether individual patients may respond more positively to creatine supplementation than others, remain to be determined. Nevertheless, these studies show that creatine supplementation has been used to treat children and adults with neurodegenerative conditions and is apparently safe and well-tolerated when taking up to 30 g/day for 5 years in these populations. Ischemic heart diseaseFraczek B, et al. Prevalence of the use of effective ergogenic aids among professional athletes. Rocz Panstw Zakl Hig. 2016;67(3):271–8. Volek JS, et al. The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreaching. Eur J Appl Physiol. 2004;91(5–6):628–37.