Imodium Instants - Fast Dissolving Tablets for On-The-Go Diarrhoea Relief in Under 1 Hour, 6 Count (Pack of 1)

Product Information

The recommended dose depends on the type of diarrhoea you have and your age. Adults (over 18), with short-term diarrhoea or IBS Do not take this product for anything other than its intended use (see section 1) and never take more than the recommended amount (see section 3). Serious heart problems (symptoms of which include fast or irregular heartbeat) have been reported in patients who have taken too much loperamide, the active ingredient in IMODIUM® Instant Melts. Children react more strongly to large amounts of IMODIUM® Instant Melts than adults. If a child takes too much or shows any of the above symptoms, call a doctor immediately. If you forget to take the medicine However, you may need to drink more fluid than usual when you have diarrhoea as fluids may be lost in the stools (see “Other important information”).

Loperamide is a medicine to treat diarrhoea (runny poo). It can help with short-term diarrhoea or irritable bowel syndrome (IBS). Sulphites can cause allergy like reactions, most commonly asthma symptoms in those with underlying asthma. Allergic rhinitis like reactions, urticaria and anaphylaxis might be observed. Loperamide is also available combined with simeticone. Simeticone is used to treat farting (flatulence or wind). Taking these medicines together helps if you have diarrhoea with painful stomach cramps and bloating. Acute and chronic studies on loperamide showed no specific toxicity. Results of in vivo and in vitro studies carried out indicated that loperamide is not genotoxic. In reproduction studies, very high doses (40 mg/kg/day – 20 times the maximum human use level (MHUL)), based on body surface area dose comparison (mg/m 2), loperamide impaired fertility and fetal survival in association with maternal toxicity in rats. Lower doses (≥ 10mg/kg/day – 5 times MHUL) revealed no effects on maternal or fetal health and did not affect peri- and post-natal development.

Patient leaflet - IMODIUM INSTANT MELTS

In individuals who have ingested overdoses of loperamide, cardiac events such as QT interval and QRS complex prolongation, torsades de pointes, other serious ventricular arrhythmias, cardiac arrest and syncope have been observed (see section 4.4). Fatal cases have also been reported. Overdose can unmask existing Brugada syndrome. If you miss a dose of loperamide, do not worry. Just take a dose after you next go to the toilet and have a runny poo. Special warnings about this medicine ¦ This medicine may make you feel dizzy, tired or sleepy. You may feel less alert, feel faint or pass out. If you’re affected do not drive or use machines. ¦ Your body can lose large amounts of fluids and salts when you have diarrhoea. You need to replace the fluid by drinking more liquid than usual. If you have acute dysentery , the symptoms of which may include blood in your stools and a high temperature.

The Imodium Classic formula calms the digestive system and restores the natural balance to bring you fast relief from diarrhea symptoms. The classic formula comes in a capsule form and treats diarrhea effectively in one dose. Imodium Original Loss of consciousness or reduced level of consciousness (passing out, feeling faint or less alert), uncoordinated movements.

Imodium Instants (2mg) - 6 Orodispersible Tablets

IMODIUM ® contains Loperamide - an ingredient that works to gently slow the digestive system into a normal rhythm. Your body can then absorb more fluids, with less fluid in the intestines and leading to a normal stool consistency. Two tablets (4 mg) initially, followed by 1 tablet (2 mg) after every loose stool, or as previously advised by your doctor. The maximum daily dose should not exceed 6 tablets (12 mg).

You should only take this medicine as you need it, following the dosage instructions above carefully. If your doctor prescribes loperamide for long-lasting diarrhoea, they will tell you how much to take. The usual starting dose is:Upon cessation, cases of drug withdrawal syndrome have been observed in individuals abusing, misusing, or intentionally overdosing with excessively large doses of loperamide. The concomitant administration of loperamide (4 mg single dose) and itraconazole, an inhibitor of CYP3A4 and P-glycoprotein, resulted in a 3 to 4-fold increase in loperamide plasma concentrations. In the same study a CYP2C8 inhibitor, gemfibrozil, increased loperamide by approximately 2-fold. The combination of itraconazole and gemfibrozil resulted in a 4-fold increase in peak plasma levels of loperamide and a 13-fold increase in total plasma exposure. These increases were not associated with central nervous system (CNS) effects as measured by psychomotor tests (i.e. subjective drowsiness and the Digit Symbol Substitution Test). capsules or tablets, or 16 spoonfuls of liquid (5ml each), if you have a prescription or buy loperamide from a pharmacy Distribution: Studies on distribution in rats show a high affinity for the gut wall with a preference for binding to receptors of the longitudinal muscle layer. The plasma protein binding of loperamide is 95%, mainly to albumin. Non-clinical data have shown that loperamide is a P-glycoprotein substrate. constipation – stop taking loperamide. If you have constipation, eat more fibre by having fresh fruit, vegetables and cereals, and drink plenty of water. Try to exercise regularly, for example by going for a daily walk or run. If this does not help, talk to your pharmacist or doctor.