skyn ICELAND Dissolving Microneedle Eye Patches with Hyaluronic Acid & Peptides: to Hydrate, Firm and Smooth Fine Lines (1 Pack)

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Chinnery,H.R.; McMenamin,P.G.; Dando,S.J. PfluegersArch. 2017, 469, 501–515. doi:10.1007/s00424-017-1947-5 Chang,M.-C.; Luo,T.-Y.; Huang,C.-Y.; Peng,C.-L.; Chen,K.-Y.; Yeh,L.-K. Biomed.Phys.Eng.Express 2020, 6, 045017. doi:10.1088/2057-1976/ab97a2 Cleanse skin thoroughly and follow the cleanser with Brightening Eye Serum, and then apply the patches. Tap them on the the skin until the microneedles begin to dissolve (10-15 seconds)

After 6 weeks my eyes are noticeably brighter, and the dark circles are disappearing which is nice to see and the lines around my eyes have softened. I’m going to continue to use weekly to maintain my results and also to see how they continue to improve over time. For this study, the team tested magnesium microneedles patches on the delicate undereye area that is susceptible to wrinkles. Adenosine for decreasing crow’s feet wrinkles (there was also 140 times less adenosine in the patch!) Undaria Pinnatifida Extract and Corallina Officinalis Extract Revitalizing natural extracts with plumping capabilities to help smooth crow’s feet and restore suppleness, while improving elasticity and tone. deGroot,A.M.; Platteel,A.C.M.; Kuijt,N.; vanKooten,P.J.S.; Vos,P.J.; Sijts,A.J.A.M.; vanderMaaden,K. Front.Immunol. 2017, 8, 10.3389/fimmu.2017.01789. doi:10.3389/fimmu.2017.01789A few studies have found that dissolving microneedle patches worked better than essences with the same ingredients: Tighsazzadeh,M.; Mitchell,J.C.; Boateng,J.S. Int.J.Pharm. 2019, 566, 111–125. doi:10.1016/j.ijpharm.2019.05.059 The length of the microneedles makes a huge difference. Longer needles can get into the dermis, which is why you might’ve seen microneedling videos online where there’s a ton of blood. But shorter microneedles can be designed to go deep enough to get past the dead stratum corneum, but not so deep that you can feel any pain or end up with any bleeding. How do dissolving microneedles work?

An alternative to methods using UV or heat is the droplet-born air blowing method (DAB). It is suitable for drug molecules that can be inactivated. In this method, polymer droplets are placed between two sheets. As the sheets are pulled apart, the droplets elongate and the resulting needle-shaped matrices are dried by the flowing air [154,155].

Before & After - Crow's Feet

Vinayakumar,K.B.; Kulkarni,P.G.; Nayak,M.M.; Dinesh,N.S.; Hegde,G.M.; Ramachandra,S.G.; Rajanna,K. J.Micromech.Microeng. 2016, 26, 065013. doi:10.1088/0960-1317/26/6/065013

Formulated using 39% Hyaluronic Acid, the patches are ideal for restoring lost moisture for a deeply hydrated finish. To help your skin absorb this all the more efficiently, both low and high molecular weights of Hyaluronic Acid has been added to ensure maximum efficacy in dispelling signs of dehydration and dryness. A nourishing Hexapeptide Complex helps you to avoid crepe-like textures, with Acetyl Hexapeptide-8 working to relax the beginnings of fine lines, delaying their progression into deeper wrinkles. Heptapeptide-7 has firming properties to lessen the impact of sagging for a more energetic look and feel. Adenosine: An anti-inflammatory ingredient that could potentially increase collagen, and has been found to decrease wrinkles. Kim YC, Park JH & Prausnitz MR, Microneedles for drug and vaccine delivery (open access), Adv Drug Deliv Rev 2012, 64, 1547-1568. DOI: 10.1016/j.addr.2012.04.005 Any discomfort or adverse events were reported by subjects during the study period. Those who experienced mild discomfort or irritation were instructed to apply the patch for an hour.

Eye Rejuvenator Ultimate Eye Patches x8, £39.95 | Vice Reversa

Pineda-Álvarez,R.A.; Bernad-Bernad,M.J.; Rodríguez-Cruz,I.M.; Escobar-Chávez,J.J. J.Pharm.Innovation 2022, 17, 71–84. doi:10.1007/s12247-020-09494-6 Since its first appearance in biomedicine, microtechnology is rapidly entering the world of pharmaceutical sciences, including pharmaceutical technology [1-4]. Due to the impressive evolution of new manufacturing techniques, it offers completely new opportunities to develop very sophisticated and precise drug delivery tools [5,6]. A large number of concepts and implemented projects, which is reflected in a large number of scientific papers, consistently pushes pharmaceutical technology to a new level of coping with various diseases, including those related to the eye [7-10].