The Koala Who Could

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Homology amongst marsupial chromosomes was determined previously from cross-species chromosome painting, which divided marsupial genomes into 19 conserved segments* and could be extrapolated to all previously G-banded marsupial karyotypes †. Koala chromosome 7 corresponds to conserved segments C7 and C8, which are located on the short arm of wallaby chromosome 7 and long arm of tammar wallaby chromosome 1 respectively, and on the short arm of opossum chromosome 1 (insert). The contigs (indicated by different colours) making up each koala supercontig and the size of the supercontigs are indicated. The tammar wallaby scaffold identifier numbers have also been provided. Gray short-tailed opossum chromosome 1 has been used as a reference as the sequence has been oriented on the gray short-tailed opossum chromosome 83. Zhang, Y. et al. Structural features of the rice chromosome 4 centromere. Nucleic Acids Res. 32, 2023–2030 (2004). Boutet, E. et al. UniProtKB/Swiss-Prot, the manually annotated section of the UniProt KnowledgeBase: how to use the entry view. in Plant Bioinformatics: Methods and Protocols (ed. Edwards, D.) 23–54 (2016).

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Faculty of Science, Health, Education & Engineering, University of the Sunshine Coast, Maroochydore, Queensland, AustraliaWe have also includes a question and answers matching activity. It might be useful to let your class cut out the questions and answers and match as many as they can. Brown, J.D. & O’Neill, R.J. The evolution of centromeric DNA sequences. Encyclopedia of Life Sciences https://doi.org/10.1002/9780470015902.a0020827.pub2 (Wiley, Hoboken, NJ, USA, 2014).

The Koala Who Could - Teaching Ideas

These authors contributed equally: Rebecca N. Johnson, Denis O’Meally, Zhiliang Chen, Marc R. Wilkins, Peter Timms, Katherine Belov. Benson, G. Tandem repeats finder: a program to analyze DNA sequences. Nucleic Acids Res. 27, 573–580 (1999). Understanding the genetics of host resistance to chlamydia and the etiology of the retrovirus will help inform the development of vaccines against both diseases, as well as translocation strategies. Genome-informed conservation

Acknowledgement:

Wang, J. COANCESTRY: a program for simulating, estimating and analysing relatedness and inbreeding coefficients. Mol. Ecol. Resour. 11, 141–145 (2011). Langmead, B. & Salzberg, S. L. Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357–359 (2012). The long-read-based genome enabled the de novo assembly of complex, highly duplicated immune gene families and comprehensive annotation of immune gene clusters 53, 57, 58. These include the major histocompatibility complex ( MHC) 59, as well as T cell receptors ( TCR), immunoglobulin ( IG) (Supplementary Fig. 9, Supplementary Tables 17 and 18, and Supplementary Note), natural killer cell (NK) receptor 58 and defensin 60 gene clusters. Together these findings provide a starting point for new disease research and allow us to interrogate the immune response to the most significant pathogen of the koala, C. pecorum.