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Cranberry Capsules 35,000mg High Strength - with Probiotics/Bio Cultures and Vitamin C - 150 Capsules - Advanced Cranberry Extract Supplement - Made in UK by VitaBright

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E. coli is a rod Gram-negative bacterium that colonizes the gastrointestinal tract of humans and animals after birth, forming part of the natural bowel microbiota. In addition, it can be an opportunistic pathogen that uses the intracellular environment to survive and protect itself against the action of antibiotics. Several epidemiological, serological, and bacteriological studies revealed that UPEC is the pathogen most frequently associated with UTIs [ 40], accounting for three-quarters of all UTIs among outpatients [ 41, 42]. These bacteria have evolved a multitude of virulence factors and strategies that facilitate bacterial growth and persistence within the adverse settings of the host urinary tract. Bianco, L., Perrelli, E., Towle, V., Van Ness, P. H., and Juthani-Mehta, M. Pilot randomized controlled dosing study of cranberry capsules for reduction of bacteriuria plus pyuria in female nursing home residents. J Am.Geriatr Soc 2012;60(6):1180-1181. View abstract. Hess, M. J., Hess, P. E., Sullivan, M. R., Nee, M., and Yalla, S. V. Evaluation of cranberry tablets for the prevention of urinary tract infections in spinal cord injured patients with neurogenic bladder. Spinal Cord. 2008;46(9):622-626. View abstract.

Fatel ECS, Rosa FT, Alfieri DF, et al. Beneficial effects of fish oil and cranberry juice on disease activity and inflammatory biomarkers in people with rheumatoid arthritis. Nutrition 2021;86:111183. View abstract. Raz, R., Chazan, B., and Dan, M. [Cranberry juice and urinary tract infection]. Harefuah 2004;143(12):891-4, 909. View abstract. Konowalchuk, J. and Speirs, J. I. Antiviral effect of commercial juices and beverages. Appl.Environ.Microbiol. 1978;35(6):1219-1220. View abstract.Coupled with their potent antioxidant and anti-inflammatory properties, cranberries may help lower the risk of some of the most common types of cancers. That’s why they are considered cancer-fighting foods. 4. Improve Immune Function Although the amount of oxalates found in cranberries is relatively low, they are able to increase the amount of both oxalates and calcium in the urine, resulting in urine with increased concentrations of calcium oxalate. Final Thoughts Frequently, cranberries are processed into products such as juices, canned sauces, sugary jams and sweetened dried cranberries. This may make them convenient, but it also depletes them of their nutritional value and cranks up the sugar content. It’s a much healthier idea to cook your own cranberries from scratch if you can. This allows you to get the most nutrients possible and avoid excessive sugar intake. Fanos, V., Atzei, A., Zaffanello, M., Piras, A., and Cataldi, L. Cranberry and prevention of urinary tract infections in children. J Chemother. 2006;18 Spec no 3:21-24. View abstract.

According to the anatomical location of the bacteria, UTIs are categorized as pyelonephritis and kidney infection when they affect the upper part of the urinary tract (ureters and kidney parenchyma), and as cystitis and urethritis when they affect the bladder or urethra (lower infection tract). Clinically, uncomplicated UTIs affect healthy individuals without urinary tract anomalies, while UTIs associated with factors that compromise the urinary tract or host defense are referred as complicated UTIs, including urinary obstruction or retention caused by neurological disease, renal failure or transplantation, pregnancy and the presence of foreign bodies such as kidney stones, indwelling catheters or other drainage devices [ 5]. Among the most common symptoms of UTIs as cystitis, there is a frequent and urgent need to urinate and pain or burning sensation in the urethra during urination. Urine is usually cloudy, sometimes even pink color due to the presence of blood. If infection rises to the kidneys, patients could also be suffer fatigue, fever, nausea and muscle and abdominal pain [ 6]. Pyelonephritis is usually a more serious problem as it can lead to irreversible kidney damage or sepsis [ 7]. Cho A, Eidelberg A, Butler DJ, et al. Efficacy of Daily Intake of Dried Cranberry 500 mg in Women with Overactive Bladder: A Randomized, Double-Blind, Placebo-Controlled Study. J Urol. 2020:101097JU0000000000001384. View abstract.

Micro Ingredients D-Mannose with Cranberry

McMurdo, M. E., Bissett, L. Y., Price, R. J., Phillips, G., and Crombie, I. K. Does ingestion of cranberry juice reduce symptomatic urinary tract infections in older people in hospital? A double-blind, placebo-controlled trial. Age Ageing 2005;34(3):256-261. View abstract. You can refrigerate cranberries for up to two months, or you can freeze them for later use. Cranberries can be kept in the refrigerator for about 20 days, and they can be kept frozen for several years. Looking for frozen cranberries in grocery stores is a great idea, because frequently you are able to find them at less expensive prices and even in organic varieties. Parry, J., Su, L., Moore, J., Cheng, Z., Luther, M., Rao, J. N., Wang, J. Y., and Yu, L. L. Chemical compositions, antioxidant capacities, and antiproliferative activities of selected fruit seed flours. J Agric Food Chem 5-31-2006;54(11):3773-3778. View abstract. In general, one serving of dried cranberries has around 25 grams of added sugar,” says O’Neill. “That’s actually how much added sugar some people can have in a day.”

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