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Saffron Oil (Crocus sativus) Essential Oil 100% Pure Natural Undiluted Uncut Therapeutic Grade Oil 0.16 Fl.Oz to 33.81 Fl.Oz by Sheer Essence (Saffron Oil (Crocus sativus) Oil, 5ML (0.16 Fl.OZ))

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PubMed: Implications of carotenoid biosynthetic genes in apocarotenoid formation during the stigma development of Crocus sativus and its closer relatives. PubMed: An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn. Nature In Bottle does not conduct or commission animal testing of any cosmetic ingredient, raw material, or formulation of any finished product in the context of Cosmetics Regulation (EC) 1223/2009. Nature In Bottle certify that Saffron Oil is compliant with the Senate Bill S4389B An Act to Amend the Environmental Conservation Law, in Relation to Prohibiting Household Cleansing Products, Cosmetic Products and Personal Care Products that Contain 1,4-Dioxane, which limits the trace concentration of 1,4-dioxane to 1 ppm. Saffron oil is made by infusing the spice in a carrier oil, which retains all of the many benefits of the spice but puts it into a much more usable form.

PubMed: Relaxant effect of Crocus sativus (saffron) on guinea-pig tracheal chains and its possible mechanisms. Saffron is readily available at most specialty markets and can be purchased as threads or in powdered form. The saffron works to help soothe, renew, and protect skin from sun-damaged skin—perfect after long days spent in the sun. The best way to draw out saffron’s unique flavor is to soak the threads in hot — but not boiling — water.PubMed: Antihyperglycemic and antioxidant activity of crocin in streptozotocin-induced diabetic rats. Saffron, also known as Kesar, is one of the most expensive spices in the world, particularly in American markets, so its concentrated oil can be even more costly, depending on where you are in the world.

PubMed: A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer's disease. Ingesting too much saffron oil can also cause other side effects such as dizziness, nausea, vomiting, diarrhea, numbness, yellowing of the skin and eyes, and even spontaneous bleeding. Out of the many, many skincare ingredients that constantly flood our inboxes and Instagram feeds, saffron is one that we've noticed popping up more often. PubMed: Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials. Registered dietitian Beth Czerwony, RD, dives into the science behind saffron and explains how to use the spice safely.In test-tube studies, saffron and its compounds have been shown to selectively kill colon cancer cells or suppress their growth, while leaving healthy cells unharmed ( 12). PubMed: Evaluation of the antitussive effect of stigma and petals of saffron (Crocus sativus) and its components, safranal and crocin in guinea pigs. To find out more about the skin-boosting benefits of saffron, including whether or not we should be slathering it all over our faces (or if we can even afford to), we spoke to board-certified dermatologist Dhaval G.

Saffron is high in antioxidants, which may help kill cancer cells while leaving healthy cells unharmed. PubMed: Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity. PubMed: Effect of ionic detergents, nonionic detergents, and chaotropic agents on polyphenol oxidase activity from dormant saffron (Crocus sativus L. Saffron may have aphrodisiac properties for both men and women and may especially help those taking antidepressants. Other studies found that taking 30 mg of saffron daily was just as effective as Fluoxetine, Imipramine, and Citalopram — conventional treatments for depression.Contact dermatitis in saffron workers: Clinical profile and identification of contact sensitizers in a saffron-cultivating area of Kashmir Valley of North India.

PubMed: Cloning, structural characterization, and phylogenetic analysis of flower MADS-box genes from crocus (Crocus sativus L. PubMed: Effects of crocetin on antioxidant enzymatic activities in cardiac hypertrophy induced by norepinephrine in rats. In many studies, saffron was shown to improve the conditions of rats with cancet possibly as a result of the high concentration of antioxidant carotenoids.PubMed: Crocetin, dimethylcrocetin, and safranal bind human serum albumin: stability and antioxidative properties. PubMed: An overview of structural features of DNA and RNA complexes with saffron compounds: Models and antioxidant activity. According to the 2018 lab study mentioned above, crocin suppresses the expression of various inflammatory proteins.

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