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Antibiotics are another common cause of acute-onset diarrhea. Antibiotic treatment often disturbs the intestinal microbiome and, by decreasing microbial diversity, can lead to a loss of microbial metabolism (resulting in osmotic diarrhea due to excessive fluid in the intestine), loss of colonization resistance (resulting in increased numbers of infections by other pathogens), and increased intestinal motility [ 25]. Up to 30% of patients who use antibiotics experience AAD [ 26]. Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults. Gut 2019; 68(Suppl 3): s1-s106. Our gut bacteria (microbiome) is fundamental to our health. It has a wide range of functions in our body and maintaining a balance of ‘good’ to ‘bad’ bacteria is key to supporting our microbiota. Williams EA, Stimpson J, Wang D, Plummer S, Garaiova I, Barker ME, et al. Clinical trial: a multistrain probiotic preparation significantly reduces symptoms of irritable bowel syndrome in a double-blind placebo-controlled study. Aliment Pharmacol Ther 2009;29:97-103. [ PubMed abstract]
50 Billion per capsule - Pro-Ven Probiotics For Antibiotics – 50 Billion per capsule - Pro-Ven Probiotics
Khalesi S, Bellissimo N, Vandelanotte C, Williams S, Stanley D, Irwin C. A review of probiotic supplementation in healthy adults: helpful or hype? Eur J Clin Nutr 2019;73:24-37. [ PubMed abstract] Ki Cha B, Mun Jung S, Hwan Choi C, Song ID, Woong Lee H, Joon Kim H, et al. The effect of a multispecies probiotic mixture on the symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Gastroenterol 2012;46:220-7. [ PubMed abstract] Lorenzo-Zuniga V, Llop E, Suarez C, Alvarez B, Abreu L, Espadaler J, et al. I.31, a new combination of probiotics, improves irritable bowel syndrome-related quality of life. World J Gastroenterol 2014;20:8709-16. [ PubMed abstract] The International Scientific Association for Probiotics and Prebiotics advises manufacturers to list the total number of CFUs—ideally for each strain—on the expiration or use by date on the product label [ 74]. The association also suggests that consumers of these supplements avoid products that list the number of CFUs at time of manufacture because this information does not account for declines in CFUs over a product’s lifespan. References
The most complete combination of friendly bacteria
Overall, research suggests that the use of multiple probiotic strains in combination as well as of probiotics containing Lactobacillus acidophilus, a mixture of Lactobacillus acidophilus and Bifidobacterium lactis, or Lactobacillus plantarum might reduce total and LDL cholesterol levels. However, more research is needed to confirm these findings. Obesity Capsules can be opened and contents sprinkled onto cold food for those who cannot swallow them whole
Probiotic Products deliver a Healthy Gut for a Healthy Life
Microorganisms ( Lactobacillus acidophilus CUL60 & CUL21, Bifidobacterium animalis subsp. lactis CUL34, Bifidobacterium bifidum CUL20), Vegetarian Capsule Shell (Hydroxypropyl Methylcellulose), Microcrystalline Cellulose, Anti-caking Agents (Silicon Dioxide, Magnesium Stearate). No allergens Szajewska H, Horvath A. Lactobacillus rhamnosus GG in the primary prevention of eczema in children: a systematic review and meta-analysis. Nutrients 2018;10. [ PubMed abstract]
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The live microorganisms used to make many fermented foods, including yogurt, typically survive well in the product throughout its shelf life. However, they usually do not survive transit through the stomach and might not resist degradation in the small intestine by hydrolytic enzymes and bile salts and, therefore, might not reach the distal gut [ 7, 8]. However, legitimate probiotic strains contained in yogurt or other foods do survive intestinal transit. Acute diarrhea is usually defined as loose or liquid stools and/or an increase in the frequency of bowel movements (typically at least three in 24 hours) [ 18]. Acute diarrhea can be accompanied by fever or vomiting, and it usually lasts no more than 7 days. Probiotics are identified by their specific strain, which includes the genus, the species, the subspecies (if applicable), and an alphanumeric strain designation [ 3]. The seven core genera of microbial organisms most often used in probiotic products are Lactobacillus, Bifidobacterium, Saccharomyces, Streptococcus, Enterococcus, Escherichia, and Bacillus. Table 1 shows examples of the nomenclature used for several commercial strains of probiotic organisms. Table 1: Nomenclature for sample commercial strains of probiotics [ 3] Genus Certain unfermented foods, such as milks, juices, smoothies, cereals, nutrition bars, and infant and toddler formulas, have added microorganisms. Whether these foods are truly probiotics depends on the microorganism levels they contain when they are eaten, whether they survive intestinal transit, and whether their specific species and strains have health effects. Dietary supplements The potential health benefits of probiotics are the focus of a great deal of scientific research. This section focuses on research on the use of probiotics to prevent or treat seven health conditions: atopic dermatitis, pediatric acute infectious diarrhea, antibiotic-associated diarrhea (AAD), inflammatory bowel disease, irritable bowel syndrome, hypercholesterolemia, and obesity. Atopic dermatitis
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