Regelle Vaginal Moisturiser - Pack of 12 Tubes

Product Information

Regelle comes in pre-filled hygienic single use applicators. The applicator is simply inserted into the vagina, squeezed, then removed and discarded. The single use applicator delivers moisture where it is needed.

It is estimated that up to 40% of your post-menopausal patients may need your advice but are simply too embarrassed to ask. Furthermore, even if you are prescribing HRT to your patients, it is shown that 25% of menopausal women who take hormone replacement therapy continue to present with the signs and symptoms of vaginal atrophy. 1 Regelle ® works by lining the inside of the vagina, providing moisturisation, lubrication and comfort 1. Easy to Use: Each box of Regelle contains either 3, 6 or 12 individual Applicators .The applicator is simply inserted into the vagina, squeezed, then removed and discarded. The single use applicator delivers moisture where it is needed. High Street Pharmacy (Boots, Lloyds) Local independent Pharmacy Supermarket Online Pharmacy Online directly from Kora Healthcare 9. Have you any Additional Comments about Regelle? Regelle works by lining the inside of the vagina, providing moisturisation, lubrication and comfort 1.Gelfand, M et al (1994) Treating Vaginal Dryness in Brest Cancer Patients: Results of Applying a Polycarbophil Moisturizing Gel. Journal of Women’s Health; volume 3, Number 6, p427-433# I found Regelle very easy to use I found Regelle easy to use I found Regelle difficult to use I found Regelle very difficult to use No opinion 8. Where would you buy Regelle?

Regelle offers immediate and clinically proven long-lasting relief from dryness and the related discomfort – and it’s so simple to apply with the hygienic one-use applicator. The fact that each application lasts for up to 3 days means that you can just get on with your life – in comfort once again. Hormonal & Life-Stage Moments Regelle has identified what we call the ‘hormonal & life-stage moments’ in a woman’s life that can cause vaginal dryness. Regelle ® is so safe patients can use it confidently for years, even decades, and with regular use some women may find that fewer applications are needed, because the dryness reduces. Opting for Regelle, which is a long-lasting vaginal moisturiser is the perfect choice for women seeking a non-hormonal solution to vaginal dryness providing continuous moisturisation for up to 3 days after each application, unlike short acting lubricants.”The polycarbophil-carbopol based vaginal gel has a high level of bio-adhesiveness capable of ensuring a prolonged moisturising action on the epithelium of the vaginal mucous membrane 2. This gel is capable of adhering to the vaginal mucous membranes thanks to the presence of two characteristic polyacid polymers having a high molecular weight and a molecular structure very similar to that of the vaginal mucous: Polycarbophil and carbopol 2. Polycarbophil is hydrophilic and provides direct cellular ‘moisturising’ action resulting from an increased flow of water molecules from outside to the inside of the cells on the surface of vaginal mucous membrane. This action creates a moist film over the vaginal wall hydrating the underlying mucosa 3. This movement of water into the cells of the vaginal epithelium is promoted by the particular unique structure of the polymers in this gel 2. Being bio-adhesive, Regelle has been shown in laboratory and clinical studies to adhere to tissue for 24-72h, resulting in diffusion of water from the gel to the underlying vaginal mucosa 3. Regelle coats the entire vaginal passage and provides immediate relief to dry cells. Once in place, Regelle delivers continuous moisture for up to 3 days per single application (as the purified water is gradually released from the polycarbophil, dry tissues are rehydrated). Dry cells are then shed naturally, leaving healthier and more supple skin beneath. Regelle is vaginal moisturiser, clinically proven to provide immediate relief from dryness and discomfort. For millions of women, vaginal dryness is a real problem that affects and interferes with their day-to-day lives. Women may experience dryness during the menopause, times of stress or as a side effect of certain medications and medical treatments. The effects of vaginal dryness vary from woman to woman, ranging from minor discomfort to painful sexual intercourse. Regardless of the level of discomfort, vaginal dryness can impact your daily life.

Regelle is a water-based intravaginal gel that is clinically proven to provide soothing, continuous moisture, giving relief from symptoms of vaginal dryness, atrophy, itching, irritation and discomfort. Regelle is a NON-hormonal preparation and can be used in conjunction with systemic hormone replacement therapy (HRT).Regular use of Regelle, once every 3 days, can help maintain vaginal health and comfort by replenishing essential vaginal moisture before and after menopause. Sadly, many women undergoing treatment for cancer do not even mention the discomfort of their vaginal dryness to their doctor for fear of sounding trivial and some will shy away from sex, which can leave their partner feeling rejected and in turn lead to more complicated relationship issues at an already difficult time. There is a wide body of clinical evidence supporting the use of Regelle ®. Please see below links to clinical papers looking at the use of polycarbophil gels for the symptomatic relief of vaginal atrophy, dryness, itching, irritation and discomfort. Painful Sexual Intercourse:Regelle provides immediate relief while rejuvenating natural secretions and improving the elasticity of vaginal walls. Immediate Relief: Regelle provides immediate comfort and long-lasting relief from symptoms of vaginal dryness.Healthcare Professional e.g. Pharmacist, GP Through a friend From an advert Internet Other 3. Prior to using Regelle, what were your symptoms? (Dryness, pain or discomfort during intercourse etc..) In a 12 month study by Bachmann et al of peri-menopausal and post-menopausal women, use of polycarbophil gel 3 times per week for one year showed that not only had vaginal health improved but this improvement was maintained as long as subjects were using the vaginal product. All parameter of the vaginal health index showed improvement including vaginal moisture, vaginal fluid volume, vaginal pH, vaginal epithelial integrity and vaginal elasticity. Overall the gel was found be well tolerated and effective in improving overall vaginal health for one year of continuous use. There were no patients who dropped out due to adverse events. Our research shows that intimate dryness can be an issue for many women at a number of ‘hormonal & life-stage moments’ during their lives – not exclusively during the menopause. Indeed, many women report suffering dryness when taking oral contraceptives, during periods of stress, during medical treatments such as chemotherapy and even during breastfeeding.

Wear breathable cotton underwear and loose clothing until symptoms improve. Do not use soaps, shower gels, bath oils or disinfectants to cleanse the vaginal area. Use Regelle for long lasting immediate relief. In a study by Gelfand et al (1994) treating vaginal dryness in breast Cancer Patients Polycarbophil Moisturising gel show that a polycarbophil vaginal moisturiser gel effectively relieves vaginal dryness in most patients without causing significant side effects. This study also showed a statistically significant reduction in mean vaginal pH and improvement in overall vaginal elasticity scores, as well as significant improvement in vaginal health measures at each monthly interval. In the VALYD study by Mincigrucci et al (2005), the use of a polycarbophil gel, either alone or in combination with HRT, brought about a significant and clinically relevant improvement in the Vaginal Health Index Score and symptoms related to vaginal atrophy. In particular, significant reductions of itching, burning and vaginal discharges were observed Dyspareunia dropped by 84%: this reduction occurred both in women taking a hormonal therapy in conjunction with a non-hormonal vaginal therapy and among women receiving only non-hormonal vaginal therapy. Due to a lengthening of the average lifespan and longer life expectancy after menopause, vaginal atrophy is destined to become a clinical problem with an increasingly greater epidemiological significance. The seriousness of this menopausal symptom should not be minimized, as vaginal dryness represents an uncomfortable problem, with physical and psychological consequences that can have a deleterious impact on the patient’s quality of life. Long Lasting: It is the perfect choice for women seeking a long-lasting non-hormonal solution to vaginal dryness. Regelle provides continuous moisturisation for up to 3 days after each application, unlike short acting lubricants.The polycarbophil-carbopol based vaginal gel has a high level of bio-adhesiveness capable of ensuring a prolonged moisturising action on the epithelium of the vaginal mucous membrane 2. This gel is capable of adhering to the vaginal mucous membranes thanks to the presence of two characteristic polyacid polymers having a high molecular weight and a molecular structure very similar to that of the vaginal mucous: Polycarbophil and carbopol 2. Polycarbophil is hydrophilic and provides direct cellular ‘moisturising’ action resulting from an increased flow of water molecules from outside to the inside of the cells on the surface of vaginal mucous membrane. This action creates a moist film over the vaginal wall hydrating the underlying mucosa 3. This movement of water into the cells of the vaginal epithelium is promoted by the particular unique structure of the polymers in this gel 2. Being bio-adhesive, Regelle has been shown in laboratory and clinical studies to adhere to tissue for 24-72h, resulting in diffusion of water from the gel to the underlying vaginal mucosa 3.
Furthermore, polycarbophil and carbopol are substances with a buffering action and their use in women experiencing menopause either naturally or as a result of surgery has led to a correction of the vaginal pH values comparable to those obtained with hormone replacement therapy 4.
The pH of the polycarbophil gel is 3.0 and it buffers to a normal vaginal pH of 3.5 to 5.0 3. Regelle, Long lasting vaginal moisturiser is clinically proven to provide immediate relief from the discomfort associated with vaginal dryness. Unlike short acting lubricants, Regelle soothes by coating the entire vaginal passage resulting in immediate relief with each application lasting up to three days. Nachtigall, L.E (1994) Comparative study: Replens versus local estrogen in menopausal women. Fertility and Sterility.Volume 61, Number 1, p 178-180. Garg et al (2001) Properties of new acid buffering bioadhesive vaginal formulation. Contraception 64. 67-75. Furthermore, polycarbophil and carbopol are substances with a buffering action and their use in women experiencing menopause either naturally or as a result of surgery has led to a correction of the vaginal pH values comparable to those obtained with hormone replacement therapy 4.