Natures Aid Vitamin E 1000iu, Natural Source, High Strength, 30 Softgel Capsules

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Because the FDA doesn’t regulate supplements in the same way it regulates drugs, third-party testing ensures that the supplement label accurately reflects what’s in the bottle. Recommended Dietary Allowance (RDA): Average daily level of intake sufficient to meet the nutrient requirements of nearly all (97%–98%) healthy individuals; often used to plan nutritionally adequate diets for individuals In supplement form, however, high doses of vitamin E might increase the risk of bleeding (by reducing the blood's ability to form clots after a cut or injury) and of serious bleeding in the brain (known as hemorrhagic stroke). Because of this risk, the upper limit for adults is 1,000 mg/day for supplements of either natural or synthetic vitamin E. This is equal to 1,500 IU/day for natural vitamin E supplements and 1,100 IU/day for synthetic vitamin E supplements. The upper limits for children are lower than those for adults. Some research suggests that taking vitamin E supplements even below these upper limits might cause harm. In one study, for example, men who took 400 IU (180 mg) of synthetic vitamin E each day for several years had an increased risk of prostate cancer. Does vitamin E interact with medications or other dietary supplements?

Weitberg AB, Corvese D. Effect of vitamin E and beta-carotene on DNA strand breakage induced by tobacco-specific nitrosam Waters DD, Alderman EL, Hsia J, Howard BV, Cobb FR, Rogers WJ, et al. Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial. J Am Med Assoc 2002;288:2432-40. [ PubMed abstract] Just keep in mind that fat-soluble vitamins can build up in your fat cells if you take too much of them, and fat-soluble vitamin toxicity may cause severe complications such as stroke or excessive bleeding ( 9). Taken as a whole, observational studies have not found that vitamin E in food or supplements offers much protection against cancer in general, or against specific cancers. [15–24] The U.S. Preventive Services Task Force’s latest review of the evidence from clinical trials on the efficacy of vitamin E for cancer also showed no benefit of these supplements on a decreased incidence of or deaths from any cancer. [2] Observational studies and clinical trials have been inconsistent, some suggesting that vitamin E supplements might lower the risk of advanced prostate cancer in smokers and a large randomized trial suggesting that vitamin E increases the risk of prostate cancer. [17,25–27]

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Choosing a product that is certified by a third-party organization like USP or NSF International can also help ensure quality and purity. Ingredients Most people don’t need a vitamin E supplement and can easily meet their needs by following a healthy, well-rounded diet. Several observational studies have revealed a potential relationship between vitamin E supplements and the risk of cataract formation. One prospective cohort study found that lens clarity was superior in participants who took vitamin E supplements and those with higher blood levels of the vitamin [ 43]. In another study, long-term use of vitamin E supplements was associated with slower progression of age-related lens opacification [ 44]. However, in the AREDS trial, the use of a vitamin E-containing (as dl-alpha-tocopheryl acetate) formulation had no apparent effect on the development or progression of cataracts over an average of 6.3 years [ 45]. The AREDS2 study, which also tested formulations containing 400 IU (180 mg) vitamin E, confirmed these findings [ 46]. Ascherio A, Weisskopf MG, O’Reilly E J, et al. Vitamin E intake and risk of amyotrophic lateral sclerosis. Ann Neurol. 2005;57:104-10.

Vitamin E supplements have the potential to interact with several types of medications. A few examples are provided below. People taking these and other medications on a regular basis should discuss their vitamin E intakes with their health care providers. Anticoagulant and antiplatelet medications Estimated Average Requirement (EAR): Average daily level of intake estimated to meet the requirements of 50% of healthy individuals; usually used to assess the nutrient intakes of groups of people and to plan nutritionally adequate diets for them; can also be used to assess the nutrient intakes of individuals The HOPE and HOPE-TOO trials provide compelling evidence that moderately high doses of vitamin E supplements do not reduce the risk of serious cardiovascular events among men and women >50 years of age with established heart disease or diabetes [ 23]. These findings are supported by evidence from the Women's Angiographic Vitamin and Estrogen study, in which 423 postmenopausal women with some degree of coronary stenosis took supplements with 400 IU vitamin E (form not specified) and 500 mg vitamin C twice a day or placebo for >4 years [ 24]. Not only did the supplements provide no cardiovascular benefits, but all-cause mortality was significantly higher in the women taking the supplements. Additionally, it seems that few or no liquid vitamin E supplements have undergone third-party testing. Dosage

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Cho E, Hunter DJ, Spiegelman D, et al. Intakes of vitamins A, C and E and folate and multivitamins and lung cancer: a pooled analysis of 8 prospective studies. Int J Cancer. 2006;118:970-8.