Vitawell Adult Vitamin D 25µg Gummies | 30 Blackcurrant Flavour Gummies | High Strength VIT D3 Formula | 1 Months’ Supply | One a Day Chewable Adult Vitamin | Bone & Immune Health | by Vitawell

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Sometimes the amount of vitamin D is expressed as International Units (IU). 1 microgram of vitamin D is equal to 40 IU. So 10 micrograms of vitamin D is equal to 400 IU. Should I take a vitamin D supplement? Advice for adults and children over 4 years old This is a fact sheet intended for health professionals. For a general overview of Vitamin D, see our consumer fact sheet on Vitamin D. Rosen CJ, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, et al. IOM committee members respond to Endocrine Society vitamin D guidelines. J Clin Endocrinol Metab 2012;97:1146-52. [ PubMed abstract] Keum N, Giovannucci E. Vitamin D supplements and cancer incidence and mortality: A meta-analysis. British Journal of Cancer 2014;111:976-80. [ PubMed abstract] A vitamin D intake of 8.5-10mcg (micrograms) per day is recommended for infants less than one year old, and an intake of 10mcg is recommended for everyone else. Experts have provided the following advice about supplementation:

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All adults should consume recommended amounts of vitamin D and calcium from foods and supplements if needed. Older women and men should consult their health care providers about their needs for both nutrients as part of an overall plan to maintain bone health and to prevent or treat osteoporosis.

Manson JE, Cook NR, Lee I-M, Christen W, Bassuk S, Mora S, et al. Vitamin D supplements and prevention of cancer and cardiovascular disease. N Engl J Med 2019:380:33-44. [ PubMed abstract]

Vitawell Adult Vitamin D 25µg Gummies | 30 Blackcurrant

Jin, J. Vitamin D and calcium supplements for preventing fractures. JAMA 2018;319:1630. [ PubMed abstract] U.S. Food and Drug Administration. Food additives permitted for direct addition to food for human consumption; vitamin D2 mushroom powder. Federal Register 2020;85:41916-20. Yao S, Kwan ML, Ergas IJ, Roh JM, Cheng T-YD, Hong C-C, et al. Association of serum level of vitamin D at diagnosis with breast cancer survival: A case-cohort analysis in the Pathways Study. JAMA Oncol 2017;3:351-7. [ PubMed abstract] Vitamin D has other roles in the body, including reduction of inflammation as well as modulation of such processes as cell growth, neuromuscular and immune function, and glucose metabolism [ 1-3]. Many genes encoding proteins that regulate cell proliferation, differentiation, and apoptosis are modulated in part by vitamin D. Many tissues have vitamin D receptors, and some convert 25(OH)D to 1,25(OH)2D.

In a subsequent investigation for 4.9 years after the study's end, women who had taken the vitamin D and calcium supplements (many of whom continued to take them) had an 18% lower risk of in situ (noninvasive) breast cancer [ 100]. However, women with vitamin D intakes higher than 15 mcg (600 IU)/day at the start of the trial and who received the supplements experienced a 28% increased risk of invasive (but not in situ) breast cancer.