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And just as there are many different types of nootropics, there are many different types of mechanisms of nootropic activity, depending on what a compound targets, which can be: DHA (as Docosahexenoic Acid from Algae): DHA is a structural omega-3 fatty acid with neuroprotective and nootropic effects. DHA has been shown to support executive function, memory and learning. A review of the “therapeut The most robust type of evidence comes from high-quality scientific studies in which the effect of a given compound is compared to that of a control. These are known as randomized placebo-controlled clinical trials. There are indeed many nootropic compounds that have been studied in this type of trial and that have shown evidence of safely enhancing cognitive function.
The combination of caffeine and L-theanine supported faster reaction time and better focus (i.e., decreased mind wandering) (Pubmed 29420994).* Substances with nootropic activity are abundant; they can be natural compounds such as vitamins, minerals, amino acids, herbs or other botanicals, mushrooms, or other dietary substances; or they can be synthetic compounds. Coleus forskohlii Root Extract is an Ayurvedic herb and a source of a unique compound called forskolin. One of forskolin’s best known functions is to influence levels of cyclic adenosine monophosphate (cAMP). Downstream from cAMP are molecules within neurons, such as brain-derived neurotrophic factor (BDNF), that are involved in synaptic plasticity, neuronal signaling and encoding of memories.* This functional role is why it’s included in Qualia Mind. Cereboost™ American Ginseng Root Extract: A ginseng root extract standardized for ginsenoside content. Ginsenosides are thought to be responsible for many of the adaptogenic (i.e., stress and fatigue support) and health-promoting properties associated with ginseng. Cereboost™ is known to enhance attention accuracy, working memory, and secondary memory. N-acetyl-L-tyrosine (NALT) is an acetylated form of the amino acid L-tyrosine. It is used as a nootropic because it acts as a precursor for the important brain neurotransmitter dopamine.* Dopamine has a large role in brain activities linked to reward, motivation, and pleasure, and plays a crucial part in modulating focus, motivation, cognitive flexibility, and emotional resilience. It’s also one of the main regulators of motor control and coordination of body movements, so can be important for exercise and muscle performance. Supplying NALT (or other sources of L-tyrosine) may be especially important to support performance during stress or cognitively demanding tasks.*
What Are the Benefits of Qualia?
DL-Phenylalanine: DLPA is a mixture of two forms of the essential amino acid phenylalanine, the naturally occurring L-phenylalanine and the synthetic D-phenylalanine with nootropic effects. DLPA enhances mood and can aid in cognitive performance.
We included vitamin B6 in Qualia Mind to support the production of brain energy and neurotransmitter molecules. We used the P5P form, because it is the bioactive form of vitamin B6; requiring less metabolic “work” to be used as coenzyme in vitamin B6-dependent enzyme reactions. The reason that the amount of vitamin B6 in Qualia Mind is much higher than the daily value is because this dose has supported healthy brain volume during aging and is within the nootropic range for neurotransmitter function, energy and mood.* The term nootropic was coined in 1972, originally in French as nootrope, by the Romanian psychologist and chemist Corneliu E. Giurgea. The term is derived from the Greek words nous (mind) and trepein (turn, bend), therefore meaning something like “mind-bender”. Corneliu Giurgea was the scientist who pioneered early nootropics that were believed to act as cognitive enhancers.
On a Mission – Who is Qualia For?
QUALIA MIND combines 28 ingredients that have been carefully selected to support mental energy, alertness, attention, concentration, focus, memory, mood, motivation, and overall cognitive performance. We are the only company utilizing complexity systems science to approach formulation. Meaning we consider the entire ecosystem of the body when developing our formulas. This results in a supplement that supports cognition and upregulates the entire body for well-being. L-Theanine: L-Theanine is an amino acid analog of glutamate and glutamine found in green tea from Camellia sinensis with neuroprotective effects. L-Theanine has anxiolytic activity and studies suggest that it may aid memory. Its main cholinergic ingredient, Citicoline, increases acetylcholine to energize brain cells, increases focus, expedites processing speed, and improves short-term memory.
Nootropics were originally defined (in very technical terms) as compounds that “characteristically interfere with the higher telencephalic integrative activity by a direct and selective action.” [1–3] In simpler terms, this means they are compounds that selectively influence higher brain functions, i.e., cognition and behavior.Nootropics are substances that enhance cognitive function and performance in healthy individuals. Nootropics do so by supporting and protecting, either directly or indirectly, the functional and structural status of the brain. Cognition relies on the proper function of an intricate network of neurons communicating through synapses and using neurotransmitters as messengers, assisted by glial cells that structurally and functionally support and protect them, and fueled by a steady blood supply of oxygen and nutrients that sustain their high energy demand. Another type of evidence comes from pre-clinical studies which are carried out in research animals or in vitro (i.e., using cells or fragments of tissues in which pathways and mechanisms can be studied). Although these do not provide the robust evidence of working in humans that a placebo-controlled trial would, they may provide proof of mechanism and proof of principle, i.e., they may show that a given compound targets a certain process or pathway of interest in such a way that may potentially lead to the enhancement of cognitive function. There are many nootropics whose use, and our understanding of how they function in the brain, is based on this type of evidence. Phosphatidylserine: Phosphatidylserine is a naturally occurring aminophospholipid found in high concentrations in the brain. Studies indicate its ability to support mental processing speed and accuracy, attention and working memory. Pyrroloquinoline quinone (PQQ) is thought of as a non-vitamin growth factor, influencing metabolism and the expression of some genes and appears to be essential for healthy growth and function. PQQ also plays roles in promoting healthy gut microbiome, immune system function, antioxidant defenses, and cognitive function. In the brain, it appears to be especially important in supporting healthy memory and cognition with aging. Some of the best food sources include soy, spinach, parsley, and kiwifruit.
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