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g. rash, urticaria, allergic dermatitis), dysuria, urinary retention (most likely to occur in those with bladder outlet obstruction, such as prostatic hypertrophy).
A mother-of-one who was throwing up coffee-coloured bile died from liver failure after unintentionally overdosing on paracetamol by drinking too much Lemsip. Phenylephrine should be used with care in patients with closed angle glaucoma and prostatic enlargement.Severe hypertension may need to be treated with alpha blocking medicinal products such as phentolamine.
British Soap Awards are CANCELLED: ITV make surprise announcement ceremony will not take place next year. An overdose of paracetamol is dangerous and capable of causing serious damage to the liver and kidneys.It is reported to have less tachycardia and pressor activity and central nervous system effects that ephedrine. The drug is rapidly and widely distributed throughout the body and is eliminated from plasma with a T 1/ 2 of approximately 2 hours. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. However the amount required to produce serious phenylephrine toxicity would be greater than that required to cause paracetamol-related liver toxicity.