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B Braun D5613 Wound Irrigation Solution, 350ml

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Clinician perspective on time and resource related to dressing changes. Available at https://www.wounds-uk.com/journals/issue/506/article-details/clinician-perspectives-on-time-and-resources-related-to-dressing-changes [accessed Jan 2021] In Vitro Evaluation of Polihexanide, Octenidine and NaClO/HClO-BasedAntiseptics against Biofilm Formed by Wound Pathogens

Newton H, Edwards J, Mitchell L, Percival SL. Role of slough and biofilm in delaying healing in chronic wounds: The management of biofilms with maintenance desloughing and antimicrobial therapy is fast becoming the accepted treatment strategy for chronic wounds. British journal of nursing 2017; 20(S20a): S4-S11. Surgical debridement → 3–6L NS pulse lavage → modular component exchange versus head and liner replacement after 10–15min 97% ethanol soak → PI 10% soak 5–10min → 3L NS irrigation Using the Prontosan ® Debridement Pad decreases the time it takes to conduct the wound bed preparation process, and subsequently a reduction in the soak time as you are physically removing the biofilm from the wound bed.George J, Klika AK, Higuera CA. Use of Chlorhexidine Preparations in Total Joint Arthroplasty. J Bone Joint Infect. 2017; 2:15–22. doi: 10.7150/jbji.16934. [ PMC free article] [ PubMed] [ CrossRef] [ Google Scholar] Total Knee Arthroplasty Revision Surgery in Known Cases of Prosthetic Joint Infection. [last access: 10May2021]; 2019 available at: https://www.zimmerbiomet.com/content/dam/zimmer-biomet/medical-professionals/surgical-and-cement/bactisure-wound-lavage/2656.1%20US-en%20Bactisure%20White%20Paper.pdf . [ Google Scholar] contamination as multiple organisms, including Burkholderia cepacia, P.aeruginosa, Mycobacterium abscessus, and fungal pathogens, have Royo A, Bertrand ML, Ramos L, Fernandez-Gordillo F, Guerado E. Is there still a place for continuous closed irrigation in the management of periprosthetic total knee infection? Open Orthop J. 2013; 7:205–210. [ PMC free article] [ PubMed] [ Google Scholar] The use of multiple additives with normal saline solution irrigation to improve bacterial bioburden eradication is

development by Staphylococcus epidermidis compared to an untreated control group. Zubko and Zubko (2013) reported the Staphylococcus epidermidis, Haemophilus influenzae, Pseudomonas aeruginosa, and E.coli) on orthopaedic materials such as stainless-steel screws, titanium discs, Atkin L, Stephenson J, Cooper DM. Wound bed preparation: a case series using polyhexanide and betaine solution and gel—a UK perspective. Journal of Wound Care 2020; 29(7): 380-6.Kim JH, Rimmer J, Mrad N, Ahmadzada S, Harvey RJ. Betadine has a ciliotoxic effect on ciliated human respiratory cells. J Laryngol Otol. 2015; 129:S45–50. [ PubMed] [ Google Scholar] Milne J. Wound-bed preparation: the importance of rapid and effective desloughing to promote healing. British journal of nursing 2015; 24: S52-S8. Surgical debridement → modular component exchange → 500mL PI 0.35% bulb irrigation → 1L NS pulse lavage → 1g Vancomycin deep to fascia, 1g Vancomycin superficial Goswami K, Austin MS. Intraoperative povidone-iodine irrigation for infection prevention. Arthroplasty Today. 2019; 5:306–308. a. [ PMC free article] [ PubMed] [ Google Scholar] Byren I, Bejon P, Atkins BL, Angus B, Masters S, McLardy-Smith P, Gundle R, Berendt A. One hundred and twelve infected arthroplasties treated with “DAIR” (debridement, antibiotics and implant retention): antibiotic duration and outcome. J Antimicrob Chemoth. 2009; 63:1264–1271. [ PMC free article] [ PubMed] [ Google Scholar]

Haddad FS, Sukeik M, Alazzawi S. Is single-stage revision according to a strict protocol effective in treatment of chronic knee arthroplasty infections? Clin Orthop Relat Res. 2015; 473:8–14. [ PMC free article] [ PubMed] [ Google Scholar] Physically deconstructs the protective EPS matrix, making pathogens more susceptible to traditional antibiotics and the body's normal defense mechanism. Wound lavage assists with mechanical removal of organisms. Prontosan Irrigation Solution. B.Braun; [last access: 1May2021]. available at: https://www.bbraunusa.com/en/products/b4/prontosan-irrigationsolution.html . [ Google Scholar] Guest JF, Fuller GW, Vowden P. Cohort study evaluating the burden of wounds to the UK’s National Health Service in 2017/2018: update from 2012/2013. BMJ Open 2020;10:e045253. doi:10.1136/bmjopen-2020-045253 Ruder JA, Springer BD. Treatment of Periprosthetic Joint Infection Using Antimicrobials: Dilute Povidone–Iodine Lavage. J Bone Joint Infect. 2017; 2:10–14. doi: 10.7150/jbji.16448. [ PMC free article] [ PubMed] [ CrossRef] [ Google Scholar]

Desired Treatment Outcomes: Cleanse | Debride | Prevent

Robson M. Treating Chronic Wounds With Hypochlorous Acid Disrupts Biofilm. Today's Wound Clinic. 2014; 8 [ Google Scholar] Surgical Lavage – NextScience. Bactisure™; [last access: 6January2021]. available at: https://www.nextscience.com/bactisure-surgical-lavage/ [ Google Scholar] Goswami K, Austin MS. Intraoperative povidone-iodine irrigation for infection prevention. Arthroplasty Today. 2019; 5:30–308. b. [ PMC free article] [ PubMed] [ Google Scholar]

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