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alteration of heart rhythm (called ‘prolongation of QT interval’ seen on ECG, electrical activity of the heart), which may, in exceptional cases, be life-threatening dolasetron administered into a vein – used in adults to treat or prevent nausea and vomiting induced by some treatments or surgery STOP taking the tablets and tell your doctor or pharmacist IMMEDIATELY if you notice any of the following serious side effects – you may need urgent medical treatment:
You or someone else in your family have a history of blood clots, as medicines like these (antipsychotics) have been associated with formation of blood clots You are diabetic or have been told you have an increased risk of having diabetes. You will need to monitor your blood sugar levels very carefully.disease of the brain (Parkinson’s disease) affecting movement (trembling, rigid posture, mask-like face, slow movements and a shuffling, unbalanced walk) low blood pressure, especially in elderly patients or when you move suddenly from lying or sitting to a standing position Before taking Nozinan Tablets, tell your doctor or pharmacist if you are taking any of the following medicines: blood clots in the veins especially in the legs (symptoms include swelling, pain and redness in the leg), which may travel through blood vessels to the lungs causing chest pain and difficulty in breathing. If you notice any of these symptoms seek medical advice immediately
This medicine is excreted into breast milk. Breast-feeding is not recommended for the duration of treatment with this medicine. tired, weak, confused, have muscles that ache, are stiff or do not work well. This may be due to low sodium levels in your blood.Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including those obtained without a prescription, as they may change the way Nozinan Tablets work. The use of this medicine can result in an excessive amount of prolactin (the hormone which causes milk to be produced) in the blood. This may be associated with a lowering of fertility.
You suffer from slow or irregular heartbeats/palpitations (torsades de pointes), or have a family history of heart problems antiarrhythmics used to treat irregular heartbeats (e.g. amiodarone, dronedarone, disopyramide, hydroquinidine, quinidine and sotalol) Do not take Nozinan Tablets and tell your doctor or pharmacist if you are taking any of the following medicines (see section 2 ‘Do not take Nozinan Tablets if’):
You have an allergic reaction. The signs include: severe itching of the skin, with a red rash or raised lumps (hives), difficulty breathing or swallowing, swelling of the face, lips, tongue or throat. you have discolouration of the skin or eyes, pain in the abdomen (stomach) or a bloated feeling, severe itching, pale or bloody stools, extreme weakness, nausea or loss of appetite. This could be caused by an infection or injury to the liver. a significant decrease in the number of white blood cells, sometimes revealed by fever and breathing difficulties (agranulocytosis)
You have been told by your doctor that you might have a stroke or you have risk factors (e.g. if you smoke or have high blood pressure, or have an excessive amount of sugar, cholesterol or fat in the blood). This medicine should be used with caution as the risk of a stroke (cerebrovascular accident) may be increased. antibiotics used to treat infections (e.g. erythromycin and spiramycin administered into a vein, and moxifloxacin)hydroxyzine – used to treat the minor symptoms of anxiety, as premedication before general anaesthesia, in nettle rash and in the treatment of some kinds of insomnia
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