Molecular Biology of the Cell

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The book was the first to position cell biology as a central discipline for biology and medicine, and immediately became a landmark textbook. Surface lower corner bumps, small tear to top of spine and small page corner folds to top of final pages at rear, tight and unmarked. As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations.

Compared to joint models based on Markov Random Fields, our model simplifies inference and hence requires shorter training and prediction times along with lower memory capacity. We now realize that to produce convincing explanations of cell behavior will require quantitative information about cells that is coupled to sophisticated mathematical/ computational approaches—some not yet invented. Importantly, the information is also very much up to date: for example, the regulation of gene expression by noncoding RNAs is explained in detail, including the roles of small and long noncoding RNAs as well as the bacterial CRISPR system.The task of condensing all this information into a reasonably concise and readable book that retains its relevance for a number of years is daunting. He recognized that the knowledge of cell biology at the time was almost entirely based on light and electron microscopy investigations, and for students this hardly integrated any new molecular biology. The actual page count will vary based on various factors such your device's screen size and font-size.

The translation of the multiple and complex steps involved in these molecular communications into equations provides quantitative information useful for predicting cellular behaviour. Educators will also find the DVD-ROM to be a rich electronic resource when compiling their lectures. For example, real-time PCR and Illumina as well as Ion Torrent sequencing methods are explained and even nanopore technology and quantum dots are mentioned, as are a wide range of methods used to analyse small molecules, proteins and cells. Whilst both books are probably targeted at advanced undergraduate and postgraduate students, I have found them invaluable as an accessible first and reliable source of information on topics I am less familiar with.In the early 1970s, he wisely spotted a latent hurdle for his long-time vision of transforming the whole biology field into a molecular science. Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page. Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. I also very much like the fact that questions are not just answered, but that there are a large number of relevant references associated with these answers.

By using the Web site, you confirm that you have read, understood, and agreed to be bound by the Terms and Conditions. This aim is certainly achieved as nearly half the book (400 pages) is taken up with information, questions and exercises grouped into sections on “terms to learn”, “definitions”, “thought problems”, “calculations”, “data handling” and, something especially appreciated by my first-year medical student daughter, “medical links”. Now in it’s 6th edition, Molecular Biology of the Cell(MBoC), a classic university biology textbook, and it’s lighter companion book, Essential Cell Biology (in its 4th edition), continue to offer students a “new and invigorating outlook on what cells are and what they do.We have added new sections, such as those on new RNA functions, advances in stem cell biology, new methods for studying proteins and genes and for imaging cells, advances in the genetics and treatment of cancer, and timing, growth control, and morphogenesis in development. Its complementary companion “The Problems Book” makes both books uniquely useful and important for student and teacher alike and together they are the most useful aids I can think of for anyone interested in learning about and understanding the molecular biology of the cell. Molecular Biology of the Cell has been described as "the most influential cell biology textbook of its time". The text is interspersed with succinct summaries, which serve to refocus the reader and there are numerous sections headed by “What We Don’t Know”, which poses questions that encourage the reader to not just take in all the information provided but inspire more detailed probing into that topic.

Our understanding of prostate cancer has increased tremendously in the past decades, with advances in molecular biology and genomics driving the way to new treatments and . This book is like a great friend - it's been around the block a few times, but it's still in fantastic shape! as published in the 2020 Edition of the Journal Citation Reports® (Clarivate), released in June 2021, 35% increase comparing the last IF.It was written in intense collaborative sessions in which the authors lived together over periods of time, [3] organized by editor Miranda Robertson, then Biology Editor of Nature. Yes, there are some fundamental biological concepts that underpin this wide ranging subject, but an appreciation of the work being carried out in this field also requires an understanding of other more specialised subject areas such as biochemistry, biophysics, bioinformatics and biomechanics. Figures enhance the text and structure/function relationships and interactions of proteins and cells are beautifully depicted.