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The Breakers Series: Books 1-3

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Very interesting too to learn that lots of animal breeders, cattle farmers, etc are using CRISPR and see lot's of opportunities to use it more. Well, what can I say about this book? I am feeling intensely emotioanl about this one and obviously, I would give it A Thousand Stars! Apart from Atul Gawande's "Being Mortal", this is another best-read for me in 2021! Such a brilliant, marvellous piece on CRISPR, its application in genome editing, diagnosing & curing diseases, and how it can be used to fight coronavirus. And most importantly, the star of this book is Jennifer Doudna - the Wonder Woman in science. With the interesting bits, there was a very heavy emphasis on the science. Too heavy in my opinion. I have a degree in science and still found myself skimming through some of the more dense material. I fear that due to this unfortunate tendency of the author’s, this book will hold limited appeal. In addition, there’s a lot of repetition with the same information and stories told over and over. Finally, the author tends to insert himself into the narrative too much, adding little value. In the history of science, there are few real eureka moments, but this came pretty close. “It wasn’t just some gradual process where it slowly dawned on us,” Doudna says. “It was an oh-my-God moment.” When Jinek showed Doudna his data demonstrating that you could program Cas9 with different guide RNAs to cut DNA wherever you desired, they actually paused and looked at each other. “Oh my God, this could be a powerful tool for gene editing,” she declared. In short, they realized that they had developed a means to rewrite the code of life."

The Breakers | Newport Mansions The Breakers | Newport Mansions

Apparently, internecine conflict between scientists in academia is BAD, and interdisciplinary team collaboration in industry ends up being pretty GOOD. Messenger ribonucleic acid (mRNA) translates genetic information embedded in DNA into instructions for protein synthesis. CRISPR and gene editing are barely getting started. Most of us will spend countless hours in coming years and decades following this science's developments. One should expect more books on genetic science than any other subjects singing peans of its impact on our health and life. It is not an exaggeration to suppose that genetic sciences' influence could be more than any other scientific revolutions so far. If the field offers equally exciting and inspirational stories of the professionals involved, like Doudna, Charpentier, and others in the book, it is even better.November 17 – December 30, 2023 Admission at 4 pm, 4:30 pm, 5 pm, 5:30 pm and 6 pm. Gates close at 6:30 pm. House & grounds close at 8 pm Pineau, Roger (1996). The Codebreakers: The Story of Secret Writing by David Kahn, internal CIA book review by Roger Pineau, ca. 1967, released to public 1996. Retrieved from [1].

The Codebreakers - Wikipedia The Codebreakers - Wikipedia

A committee of the United States Intelligence Board concluded that the book was "a possibly valuable support to foreign COMSEC authorities" and recommended "further low-key actions as possible, but short of legal action, to discourage Mr. Kahn or his prospective publishers". [3] Kahn's publisher, Macmillan and Sons, handed over the manuscript to the government for review without Kahn's permission on 4 March 1966. [3] Kahn and Macmillan eventually agreed to remove some material from the manuscript, particularly concerning the relationship between the NSA and its counterpart in the United Kingdom, GCHQ. [3] The Puzzle Palace (1982), written by James Bamford, gives a history of the writing and publication of The Codebreakers. [3] Kahn, then a journalist, was contracted to write a book on cryptology in 1961. He began writing it part-time, and then he quit his job to work on it full-time. [3] The book was to include information on the NSA and, according to Bamford, the agency attempted to stop its publication. The NSA considered various options, including writing a negative review of Kahn's work to be published in the press to discredit him. [3]Doudna si Charpentier au revolutionat domeniul in 2011 demonstrand ca poti tinti, cu ajutorul unui ghid, secventa de ADN pe care vrei sa o tai, inserand in loc o gena preferata, adica este programabil !

The Code Breaker: Jennifer Doudna, Gene Editing, and th… The Code Breaker: Jennifer Doudna, Gene Editing, and th…

Stars for The Code Breaker: Jennifer Doudna, Gene Editing, and The Future of the Human Race (audiobook) by Walter Isaacson read by Kathe Mazur. The camaraderie in the lab was not an accident: in hiring, Doudna placed as much emphasis on making sure someone was a good fit as she did assessing their research accomplishments.' M-a mai impresionat cata sustinere are cercetarea in SUA. Desi stiam, am descoperit ca este mult mai substantiala decat presupuneam. From the first chapter, I had an emotional connection to the story, as I felt grateful that Doudna had the internal fortitude not to listen to the many teachers who in various different ways insisted that "Girls don't do science." She shares that at the time it was hurtful to her, but it also stiffened her resolve and caused her to focus on her goals. She remembered telling herself "I will show you. If I want to do science, I am going to do it."Doudna: "We could create a gene gap that would get wider with each new generation," she says. "If you think we face inequalities now, imagine what it would be like if society became genetically tiered along economic lines and we transcribed our financial inequality into our genetic code." Even though much has changed since the 1960’s, women in science still experience HUGE institutional sexism. CRISPR-Cas9 systems can be ‘programmed’ relatively easily and inexpensively, to conduct ‘germline editing’ (i.e. insertion of designer DNA, or deletion of unwanted DNA) into the organism’s genetic code. The Code Breaker will be dated in a matter of months. Better explanations of the technologies involved are emerging every day in popular magazines and newspapers. The technologies themselves are becoming rapidly outdated, with the commentators re-assigning past events' importance for their impact on the future with each discovery. The scientists involved have decades more of careers even if we ignore the ballooning army of newcomers. The heroes and their associations, competitions, inspirations will likely appear utterly different over time.

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