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Naproxen was one of the four substances named in the prosecution of Industrial Bio-Test Laboratories (IBT) for fraudulent toxicology testing [47] Naproxen passed subsequent legitimate toxicology testing.

If you stop taking the drug suddenly or don’t take it at all: You may experience more pain and inflammation (swelling and damage) caused by your condition.Naproxen might make your blood pressure medications less effective. If you’re older than 65 years, combining naproxen with certain blood pressure medications may damage your kidneys. Examples of these medications include: Gaining weight is not a side effect of Naproxen. Pain killers do not generally cause weight gain. However, if you are experiencing unexpected weight gain, be certain to speak with your doctor. Is Naproxen dangerous? Prescription naproxen oral tablets may cause drowsiness. You shouldn’t drive, use machinery, or do other activities that require alertness until you know you can function as you usually would. This drug can also cause other side effects. More common side effects Coxib and traditional NSAID Trialists' (CNT) Collaboration, Bhala N, Emberson J, Merhi A, et al. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomized trials. Lancet. 2013 Aug 31;382(9894):769-79. doi: 10.1016/S0140-6736(13)60900-9. Epub 2013 May 30. http://www.ncbi.nlm.nih.gov/pubmed/23726390 Stop using Aleve and seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Common side effects include dizziness, headache, bruising, allergic reactions, heartburn, and stomach pain. [7] Severe side effects include an increased risk of heart disease, stroke, gastrointestinal bleeding, and stomach ulcers. [7] The heart disease risk may be lower than with other NSAIDs. [7] It is not recommended in people with kidney problems. [7] Use is not recommended in the third trimester of pregnancy. [7] If you take gastro-resistant tablets, swallow them whole, with or after food. Do not crush or chew them. A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. Travel

Older patients, patients with type 2 diabetes or with a history of stomach ulcers, kidney problems or at risk for heart disease are more likely to suffer from NSAID-related complications such as GI side effects, cardiovascular events, and kidney toxicity. NSAIDS should be avoided, but if deemed necessary, their usage should be monitored by a doctor. low red blood cells (anemia) - pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or Twice daily dosing is recommended; more frequent dosing does not necessarily improve the response to naproxen.