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Codival ADP (Oregano Emulsion) 60Pearls 300g

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GP-Q: conceptualization and writing—original draft. SE-R: conceptualization, project administration, and funding acquisition. JP: conceptualization, resources, and funding acquisition. MA and BV-L: conceptualization, resources, writing—review and editing, supervision, project administration, and funding acquisition. All authors contributed to the article and approved the submitted version. Funding

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results. References Bastola, K.P.; Guragain, Y.N.; Bhadriraju, V.; Vadlani, P.V. Evaluation of standards and interfering compounds in the determination of phenolics by Folin-Ciocalteu assay method for effective bioprocessing of biomass. J. Anal. Chem. 2017, 8, 416–431. [ Google Scholar] [ CrossRef][ Green Version] Baranauskaitė, J.; Jakštas, V.; Ivanauskas, L.; Kopustinskienė, D.M.; Drakšienė, G.; Masteikova, R.; Bernatonienė, J. Optimization of carvacrol, rosmarinic, oleanolic and ursolic acid extraction from oregano herbs (Origanum onites L., Origa-num vulgare spp. hirtum and Origanum vulgare L.). Nat. Prod. Res. 2015, 30, 672–674. [ Google Scholar] [ CrossRef] [ PubMed] Guo, Y.Q. Relationship between the zeta potential and the chemical agglomeration efficiency of fine particles in flue gas during coal combustion. Fuel 2018, 215, 757–765. [ Google Scholar] [ CrossRef]Burger, T.; Zhang, Y. Recent progress in the utilization of pea protein as an emulsifier for food applications. Trends Food Sci. Technol. 2019, 86, 25–33. [ Google Scholar] [ CrossRef] Munhuweyi, K.; Caleb, O.J.; van Reenen, A.J.; Opara, U.L. Physical and antifungal properties of β-cyclodextrin microcapsules and nanofibre films containing cinnamon and oregano essential oils. LWT 2018, 87, 413–422. [ Google Scholar] [ CrossRef]

Due to the antioxidant and biocompatibility properties of lignin, lignosulfonate MPs were successfully developed by Piombino et al. (2020) to encapsulate thymol and its derivatives as topical systems with antimicrobial properties for cosmetics through environmental friendly sonication procedures. Results showed that more than 40% of each substrate was properly encapsulated, except for 2,4-dibromothymol, showing the best encapsulation efficiencies for the mono-brominated thymol derivative (76%). To test the suitability of these systems as dermal agents, the in vitro release of the derivatives from the MPs in solutions simulating skin pH (acetate buffer at pH 5.4) were performed, showing a slow-release, especially for O-methylated compounds, that was dependent on the inherent lipophilicity of each compound. Thymol-loaded poly(lactic- co-glycolide) (PLGA) MPs have also been demonstrated to be suitable microcarriers of thymol improving thermal and storage stability and controlling thymol release ( Zhu et al., 2019). In addition, the antibacterial properties of the MPs against E. coli and Staphylococcus aureus were demonstrated by the disruption of their cytoplasmic membrane, since the porous structure of the MPs enhances the permeation of thymol into bacteria. The antibacterial effect was confirmed by adding the loaded MPs into naturally contaminated milk and observing that the growth of bacteria was suppressed by thymol-loaded MPs. OEO Nanoencapsulation Singleton, V.L.; Rossi, J.A. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am. J. Enol. Vitic. 1965, 16, 144–158. [ Google Scholar]

Journals

AOAC International. Official Methods of Analysis (Method 930.15); Association of Official Analytical Chemists: Arlington, VA, USA, 1995. [ Google Scholar] Ivanković, M. Optimizing the Conditions of Emulsification of Biologically Active Compounds Originating from the Lamiaceae Family. Bachelor’s Thesis, University of Zagreb, Zagreb, Croatia, 30 September 2020. [ Google Scholar]

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