Joined in 2023 
82 
63 About this deal
After neutralization, the skin may be rinsed or cleansed gently. Following application, an initial erythema might become red and is often accompanied by edema. Stringy or patchy light frosting (Level I) might subsequently develop, indicating epidermolysis with separation of the epidermis from the underlying dermis. Development of frank or uniform frosting (≥Level II) indicates deeper destruction into the dermis and is not desirable, as this is meant to be a relatively superficial peel. Exfoliation typically occurs over several days, and reepithelialization is complete within 7 to 10 days. 1 , 2 , 7 , 8 , 9 , 21 Inflammatory acne lesions can be effectively treated and prevented due to the antibacterial benefits provided by this acid. It can kill Cutibacterium acnes (formerly Propionibacterium acnes) a known precursor to acne development. Van Scott EJ, Yu RJ. Hyperkeratinization, corneocyte cohesion, and alpha hydroxy acids. J Am Acad Dermatol 1984;11(5Pt1):867-79.. View abstract. There are plenty of ways to build glycolic acid-based products into your routine. The best way to determine which works best for you, is to determine why you’re interested in using glycolic acid in the first place. Here are some ways this powerhouse ingredient can be put to good use:
Abels C, Kaszuba A, Michalak I, Werdier D, Knie U, Kaszuba A. A 10% glycolic acid containing oil-in-water emulsion improves mild acne: a randomized double-blind placebo-controlled trial. J Cosmet Dermatol. 2011 Sep;10(3):202-9. View abstract. Raised scars can be diminished in appearance due to glycolic acid’s keratolytic quality. When used in low concentrations with retinoic acid, one study demonstrated a significant improvement in 91% of the patients. On its own, it’s unlikely to cause a severe reaction. However, you should take care when using glycolic acid – or indeed any AHAs – with other skincare products, as it may potentially irritate the skin. Lactic acid, which is structurally identical to glycolic acid with the exception of an additional methyl group at the β-carbon end, has a lower pKa and thus a lower pH than glycolic acid at equivalent concentrations, allowing for efficient chemoexfolation at lower concentrations. 35 – 37 , 40 Clinically, lactic acid has demonstrated comparable efficacy in the treatment of photodamage, superficial hyperpigmentation, and fine rhytides compared to standard glycolic acid peels.Because lactic acid has a lower pH than glycolic acid, a lower concentration is often used to achieve an equivalent depth of keratocoagulation compared to glycolic acid, which allows a favorable side effect profile and recovery time. As with glycolic acid, neutralization is necessary, and exfoliation after treatment typically occurs over several days with complete reepithelialization in 7 to 10 days. 1 , 2 , 17 , 27 , 28 , 39 Self-precipitation of the peeling agent accounts for little penetration and a good safety profile, thus reducing the risk of postpeel hyperpigmentation, especially in the darker skin types.[ 16] These features have made salicylic acid peel superior to glycolic acid peel in comparative studies conducted earlier in dark-skinned individuals. Studies have also shown beneficial effect of salicylic acid peel in postinflammatory pigmentation in dark-skinned individuals.[ 16, 17] Similar effect on postinflammatory hyperpigmentation was noted in this study. Salicylic acid decreases postacne hyperpigmentation by its anti-inflammatory effects. Ahn and Kim[ 18] found salicylic acid to have a whitening effect on the skin as well. Mandelic acid also has a beneficial effect in improving skin pigmentation.Beyond these more specific routines, there are a few other things you might like to consider when choosing the glycolic product that works best for your skin type. Night creams should be progressively applied. Begin using them once a week, followed by every 3 nights if your skin responds well to the initial inclusion in your regimen. Peeling treatments can be applied once or twice a week for a gentle, exfoliating action. They don’t necessarily need to be used every single day to be effective. In many cases, less is more. Dermatologists use higher concentrations of glycolic acid (20 to 70%) to remove several layers of skin over a short, set period of time. In your at home products, lower concentration glycolic acid products used over a more frequent period of time have been shown to be just as effective. It’s all about what works best for you, your skin type, and your routine Salicylic and pyruvic acids.In addition to the aforementioned AHAs, salicylic acid, a beta-hydroxy acid, and pyruvic acid, an alpha-keto acid, have also demonstrated clinical efficacy as single agents for superficial peeling when used in lower concentrations or with monolayer application technique. 1 – 3 , 21 , 32 – 34 If you’re more focused on solving acne scarring than actual inflammation, there’s no need to adhere to a daily schedule. Committing yourself to a light glycolic acid peel routine once or twice a week will help to reduce scarring and give your skin a healthy glow.
Campos V, Pitassi L, Kalil C, Gonçalves Júnior JE, Sant'Anna B, Correia P. Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris. J Cosmet Dermatol 2021;20(6):1766-1773. View abstract. As with all acids, glycolic comes with some baggage. And due to its low molecular weight, incorrect use can actually prove more problematic than it might with other AHAs. Dr Zamani says: “Overusing glycolic acid can leave the skin red, dry and more sensitive to the sun. This can cause premature ageing, thinning of the skin and heightened risk of pigmentation.” In one study, it was found a high concentration of glycolic acid significantly improved skin texture as well as hyperpigmentation of follicles in patients with keratosis pilaris. Since the best products for you will depend on your skin type, you should always consult your dermatologist first. If your skin is more sensitive or dry, look for products that have a lower glycolic acid percentage (around 5%). The kit contains L’Oréal Paris’s Revitalift Laser Renew Anti Ageing Glycolic Peel Pads and L’Oreal Paris’s Laser Renew Advanced Anti Ageing Care SPF 20. The former of the two products contains ready-to-use glycolic acid pads that are perfect for incorporating daily exfoliation into your routine. The second product is all about protecting your fresh new skin cells from the harmful effects of UVA/UVB rays. This cream is enriched with a 3% concentration of Pro-Xylane™ and LHA, all wrapped up in a triple action formula that when combined helps to refirm, refine, and shield your skin from damage. A kit like this is perfect for daily use. We’re pretty sure you’ll notice a transformation in your skins luminosity and smoothness in no time at all.In 15 cases of melasma (epidermal: 80%; dermal: 13.3%; and mixed: 6.6%), 52.5% GA concentration was applied for 3 minutes. There was good to fair response in patients with epidermal and mixed melasma, while no significant improvement was seen in dermal melasma. 24 The minor side effects reported are: erythema, stinging sensation, sensation of pulling of facial skin, mild burning, and transient postinflammatory hyperpigmentation. Unbuffered GA can cause erosive blisters and scarring. 40 , 58 In rare cases, hypopigmentation, persistent erythema, and flare-up of pimples have been reported. 24 , 36 , 59 In a pilot study by Burns et al, postinflammatory hyperpigmentation was treated with a series of GA peels in skin types IV–VI. No adverse effects were reported in dark skin, and the GA peel proved to be efficacious. 41 This echoed the study by Grover and Reddu, in which skin types III–V showed overall improvement of skin texture in almost all patients. 24 In another study by Atzori et al, 70% GA was used in comedonic acne, papulopustular, and nodular/cystic acne. While comedones improved rapidly, papulopustular acne improved after six peel sessions, and nodulocystic lesions required ten sessions at three-week intervals. A significant improvement of coexisting post-acne superficial scarring was noted. Patient tolerance and compliance were both found to be excellent. 22
As both products can cause dryness, ensure you use a rich moisturizer after your treatment. Scar reduction Ishfaq F, Shah R, Sharif S, Waqas N, Jamgochian M, Rao B. A comparison of microneedling versus glycolic acid chemical peel for the treatment of acne scarring. J Clin Aesthet Dermatol 2022;15(6):48-52. View abstract.Kessler et al compared 30% GA versus 30% salicylic acid (SA) peels in 20 patients with mild to moderate acne, using a split-face design. Peels were performed every 2 weeks for a total of six treatments. Both peels improved acne. However, the authors found that the SA peel had better sustained efficacy (ie, number of acne lesions, and improvement rating by blinded evaluator) and fewer side effects than GA, presumably due to the greater lipophilicity of SA. The authors agreed with the impression that SA peels are better tolerated than GA peels in acne patients. 25 Baumann LS, Oresajo C, Yatskayer M, Dahl A, Figueras K. Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris. J Drugs Dermatol. 2013 Mar;12(3):266-9. View abstract. Even if you’re not hugely into skincare (i.e. if a simple cleanse, tone, moisturise is enough to please you), it’s likely you’ve come across the words ‘glycolic acid’ plastered across products. From the super luxe to drugstore regulars, most of the major beauty brands have an impressive glycolic offering. As a leave-on treatment, I don't recommend using glycolic acid every day because it can cause excessive irritation," says Wnek. "Incorporate it slowly into your routine and work your way up to every other day or every two days, if tolerated."
Great Deal 
New Comment