3 Sets Amniotic Fluid Test Strip Maternity Home High Sensitivity Feminine PH Test Strips for Women

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Even after the amniotic fluid has been examined, many pregnant women notice a certain feeling of pressure in their abdomen. However, this will subside a few minutes after the procedure. Notice This test involves putting a drop of fluid obtained from the vagina onto paper strips containing Nitrazine dye. The strips change color depending on the pH of the fluid. The strips will turn blue if the pH is greater than 6.0. A blue strip means it’s more likely the membranes have ruptured. Today, an examination of the amniotic fluid is already considered a routine procedure. Nevertheless, complications can occur under certain circumstances. In rare cases, a miscarriage or premature rupture of the membranes may occur. Contractions of the uterus, bleeding, or injuries to the unborn baby are possible if necessary. However, the number of corresponding cases is vanishingly small. What If The Test Is Positive? Naturally, expectant parents hope that the results of the examination of the amniotic fluid will be negative. In case of a positive result, it is sometimes necessary to terminate the pregnancy. However, before taking such a step, the pregnant woman concerned is given detailed and very intensive counseling. A green or green-yellow color means that your amniotic fluid has been colored by meconium. This happens when your baby has had a bowel movement. Make sure to let your OB or midwife know as this might affect steps they take during delivery to keep your baby safe. Odor

Amniocentesis - Mayo Clinic Amniocentesis - Mayo Clinic

Genetic testing. Genetic amniocentesis involves taking a sample of amniotic fluid and testing the DNA from the cells for diagnosis of certain conditions, such as Down syndrome. This might follow another screening test that showed a high risk of the condition. Some women describe experiencing a pain similar to period pain or feeling pressure when the needle is taken out. In a case-control prospective study, Marcellin et al (2011) compared the performance of2 rapid tests for the diagnosis of PROM based on the detection of IGFBP-1 and PAMG-1 in cervico-vaginal secretions. Pregnant women between 24 and 41(6/7) weeks' of gestation, consulting for profuse amniotic fluid loss (group 1) or for other reasons without any rupture of membrane (group 2) were included in the study. Successively, AmniSure test (PAMG-1) without speculum, and then Actim Prom test (IGFBP-1) during speculum examination were performed during the same visit. A total of 80subjects (40 in each group) were included between 25(1/7) to 41(1/7) weeks of gestation. AmniSure diagnostic test demonstrated a sensitivity and specificity of 95 % (82.4 to 99.4) and 94.8 % (79.3 to 98), respectively and a PPVand NPVof 95 % (84.7 to 100) and 94.8 % (87.9 to 100), respectively. Actim Prom test demonstrated a sensitivity and specificity of 97.5 % (85.7 to 100) and 97.4 % (82.4 to 99.4), respectively and aPPV and NPV of 97.5 % (88.5 to 100) and 97.4 % (92.5 to 100), respectively. The authors concluded that both tests have similar performance to diagnose PROM. McElrath T. Midtrimester preterm premature rupture of membranes. UpToDate[online serial]. Waltham, MA: UpToDate;reviewed July 2015. Genetic amniocentesis can provide information about the baby's genes. Generally, genetic amniocentesis is offered when the test results might affect how to manage the pregnancy.

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Preterm PROM before the 24th week is rare. However, it often results in death of the fetus because the baby’s lungs are not able to develop properly. If the baby survives, they will often have long-term problems, including: Samples of amniotic fluid were collected during caesarean section in 41 patients. A dilution series was prepared and both tests were performed twice at each dilution. Sensitivity, detection limit, response time, and reproducibility of both tests were compared. Both tests' sensitivity was 100 % at dilution 1:10 and 1:20. AmniSure sensitivity was higher at dilution 1:40 and 1:80 (p < 0.05). In 29 of 40 cases, AmniSure had a lower detection limit than Actim PROM. AmniSure response times were shorter and reproducibility was higher than Actim PROM (p < 0.05). The authors concluded that AmniSure had a lower detection limit of amniotic fluid than Actim PROM, with a shorter response time, a higher sensitivity, and a better reproducibility. Seventeen patients (8.7 %) were test positive: In this group, 3 patients delivered before 34 weeks' gestation, whereas none delivered at less than 32 weeks. The sensitivity, specificity, PPV and NPV of the test for spontaneous preterm delivery less than 34 weeks were 14 % (95 % confidence interval [CI]: 3 to 37 %), 92 % (86 to 95 %), 17 % (4 to 44 %) and 90 % (84 to 93 %), respectively, with a positive and negative likelihood ratio of 1.79 (0.56 to 5.74) and 0.93 (0.78 to 1.10). The authors concluded that in the second trimester, rapid cervical phIGFBP-1 testing in asymptomatic twin pregnancies has a poor performance in predicting spontaneous preterm delivery. Lee and colleagues (2009) stated that the AmniSure test is approved for the diagnosis of PROM. Yet, a fraction of patients with a positive test have intact membranes by sterile speculum examination. The objective of this study was to determine the clinical significance of this finding. The study population consisted of4 groups of nulliparous women at term: The pH ofvaginal secretions is generally 4.5 to 6.0, whereas amniotic fluid usually has a pH of 7.1 to 7.3; however, false-positive results may occur as the result of contaminationwith blood or semen, alkaline antiseptics, or bacterial vaginosis andfalse-negative results can occur with prolonged leakage and minimal residual fluid. In unusual cases in which the diagnosis remains unclear after physical examination, ultrasonography may be helpful. When ultrasonography is inconclusive,transabdominal instillation of indigo carmine dye followed by observation for passage of blue fluid from the vagina will confirm ROM unequivocally.The indigo carmine testincludes amniocentesis and instillation of dye into the amniotic cavity. Leakage of blue stained fluid into the vagina within 20 to 30 minutes, as evidenced by staining of a tampon, is regarded as a definitive diagnosis of PROM. Management of ROM hinges on knowledge of gestational age and evaluation of the relative risks of preterm birth versus intrauterine infection, abruptio placentae, and cord accident that could occur with expectant management (RCOG 2006; Medina and Hill, 2006; ACOG, 2007).

Amniocentesis - NHS

The authors stated that this study was limited due to the small sample size (n = 81). Furthermore, since this study was observational, these investigators could not control measurements for variables such as maternal positioning, fluid management, maternal anxiety, timing of bearing down, etc. Lastly, these researchers did not examine the change in hemodynamic parameters in different settings of maternal and obstetrical complications such as previous cardiovascular disease and acute bleeding. Functional Placental Magnetic Resonance Imaging for Evaluation of Infection/Inflammation in Women with PPROM Neil PR, Wallace EM. Is Amnisure ®useful in the management of women with prelabour rupture of the membranes? Aust N Z J Obstet Gynaecol. 2010;50(6):534-538. After amniocentesis, your health care provider will continue using the ultrasound to monitor your baby's heart rate. You might have cramping or mild pelvic pain after an amniocentesis. Amniocentesis is not offered to all pregnant women. It's only offered if there's a higher chance your baby could have a genetic condition. When you’re pregnant, you may feel like everything leaks: Your bladder becomes fuller faster, and you may leak urine. Your vaginal tissues also may produce extra fluid to help your baby pass more easily. So it can be difficult to determine if fluid is urine, amniotic fluid, or vaginal fluid.

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https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2013/11/definition-of-term-pregnancy Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Yonsei University Health System, South Korea.