Smecta*60 Sachets. A New Step in Treating Diarrhoea -Powder for Oral Suspension.

Product Information

DIRECTIONS FOR USE AND DOSAGE (summary) This medication is taken preferably after meals for esophageal pain, between meals for other indications. It can be mixed with water or semi-liquid food. For babies, the contents of the sachet can be diluted in a 50 ml bottle. When applying Smecta for children one should use the following instructions for the preparation of the drug. Smecta must be dissolved in 50 ml of warm water. If the child refuses to take Smecta, then it can be mixed with mashed potatoes, cereal, milk mixture, fruit juice or fruit juice. It is important to list the medicines you are taking with your doctor before you intend to use Smecta to avoid drug interactions How much does Smecta medicine cost? NPRA has received a total of 9 reports with 12 adverse events suspected to be related to dioctahedral smectite/ diosmectite. Reported adverse events include rash, urticaria, angioedema and periorbital oedema. To date, no report related to lead poisoning following the use of Smecta ® has been reported to the NPRA 2. During the use of the drug, if any results are found, the drug should be stopped as soon as it is cured to avoid the risk of constipation.

Taking an excessively high dose of SMECTA 3 g ORANGE-VANILLA can cause constipation, which generally disappears when the dose is decreased or treatment is stopped. Consult your doctor or pharmacist. The Smecta powder sachet is a medicine taken preferably after meals for esophageal pain, between meals for other indications. It can be mixed with water or semi-liquid food. For babies, the contents of the sachet can be diluted in a 50 ml bottle. A balanced diet, slow chewing, elimination of difficult-to-digest foods and alcoholic beverages often help to alleviate symptoms due to acid upwelling or stomach inflammation . For children, if encountering unusual symptoms during the use of the drug such as: fever, refusing to eat, bloody stools, … should notify the doctor immediately. An allergic reaction that can manifest itself by the following signs: redness of the skin, itching, swelling of the face and throat, difficulty breathing, malaise, collapse.By reporting adverse reactions, you are helping to provide more information about the safety of the drug. Excipients for Smecta gastric dressings: Ethanol, Glucose monohydrate, Glyceryl, Gum arabic, Maltodextrin, Orange flavor, Orange flavor, Saccharin sodium, Sucrose, Silicon dioxide, Soybean lecithin, Vanilla flavor, Vanilla flavor Precaution for use with Smecta

Various guidelines are available for the treatment of acute diarrhoea in adults [ 6– 8]. Fluid intake is to be maintained, preferably with glucose-containing drinks or electrolyte-rich soup, as indicated by thirst. Oral rehydration solutions are needed in frail people only. Small light meals can be recommended, solid food intake being guided by appetite. Several treatment options are available: antidiarrhoeal therapies such as antimotility, anticholinergic, antisecretory, and antimicrobial drugs, as well as adsorbents. No studies on the ability to drive and use machines have been performed. However, the expected effect is nil or negligible. Smecta Sachet Powder is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:Therefore, before using Smecta, the patient should make a list of the medicines you are using for the doctor or pharmacist. To ensure safety when using, you should not arbitrarily take the drug, stop or change the dosage without the permission of your doctor.

You can easily find Smecta at retail pharmacies nationwide. When buying, you should talk directly with medical staff for advice on how to use and dose in the absence of a prescription from your doctor.

QUESTIONS & ANSWERS

Do not throw any medicines into drains or rubbish. Ask your pharmacist to remove any medications you are no longer using. These measures will help protect the environment. Continue feeding during diarrhea, excluding certain foods, especially raw vegetables and fruits, green vegetables, spicy dishes, as well as frozen foods or drinks,

If you are pregnant or breastfeeding, think you may be pregnant or plan a pregnancy, ask your doctor for advice or pharmacist before taking this medication. Patients attended the study centres three times: at screening (patients included in the study began treatment at once), at midstudy (day 4 or 5 after inclusion), and for a concluding examination (day 8 or 9 after inclusion). In adults: On average 3 sachets per day. In practice, the dosage can be doubled at the start of treatment. Smecta does not affect the content of vitamins, minerals and beneficial intestinal microflora. In addition, the drug has a beneficial effect on the gastric mucosa. This impact is twofold. First, Smecta fills minor defects in the mucous membrane and forms a protective layer on its surface. Secondly, the medicine prevents the negative effect of the acidic environment of the gastric juice, microbes and their toxins on the mucous membrane. All this has a preventive effect, prevents the exacerbation of diseases and the occurrence of bleeding. One of the advantages of the tool is that it acts exclusively in the field of the gastrointestinal tract. None of its components are absorbed into the bloodstream – even with diseases such as colitis and colonopathy. This means that the drug does not accumulate in the body.

Ανατομική/θεραπευτική/χημική (ATC) ταξινόμηση

The statistical analysis plan was based upon the assumption that the duration of the diarrhoea episode would be shorter than seven days for all patients, without any risk of data censure. It was therefore planned to compare mean diarrhoea durations using the Wilcoxon's test, which is perfectly adapted to this type of data. The definition of diarrhoea duration required that patients are followed after the first formed stool to confirm the end of the diarrhoea episode. This definition of recovery was selected to guarantee the clinical relevance of the primary criterion. Of note is that it was much more constraining than previous trials, which defined recovery as the first nonliquid stool. However, according to the definition of recovery used in the study, 35 patients showed diarrhoea duration longer than seven days. Since the protocol planned a seven-day followup, these patients were censored in statistical analyses. Nevertheless, a post hoc time to event analysis taking data censure into account was carried out. The Gehan-Wilcoxon test was preferred to the Logrank test because of the particular distribution of the events considered and the onset of censures during study followup. Indeed, the Gehan-Wilcoxon test is more adapted than the Logrank test to early events and late censures. Moreover the latter is based upon the assumption of proportional hazards, which is most probably not verified in this trial since the active treatment is supposed to shorten time to recovery without modifying the risk of recovery. Acute watery diarrhoea is self-resolving, even in the absence of treatment. The results of the Gehan-Wilcoxon test confirmed the effectiveness of diosmectite. These results are consistent with the primary analysis and confirm that diosmectite shortens time to recovery. Do not use this medication for long periods of time without the advice of your doctor: tests may be necessary if symptoms persist. Diosmectite may be a useful additive in the treatment of acute childhood diarrhoea. As evidence is of ‘low quality’, future research is needed with higher quality designs before any firm recommendations can be made. [2] See also [ edit ] The study included outpatient males and nonpregnant women aged 18 to 65 years in 23 primary and secondary care centres in Tunisia. Besides, the structure of the active ingredient diosmectite in Smecta is capable of absorbing other drugs and excreted if used together.