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Histamine is metabolized in your body via your DAO (diamine oxidase) enzymes. Due to genetic variations, some individuals have slower DAO enzymes. Your DAO enzymes can also become stressed from your environment or lifestyle. This can slow down histamine metabolism, leading to high histamine levels. DAO enzymes can be further slowed by leaky gut, alcohol, and certain drugs. Slow enzyme activity combined with high-histamine foods can cause high histamine levels in your body. This, in turn, can lead to increased levels of inflammation and histamine intolerance in a vicious cycle. Unlike regular probiotics, ProBiota HistaminX specifically contains probiotic species that do not increase histamine levels in the gut. Additionally, it uses acid-resistant capsules to ensure the probiotics reach the lower digestive tract intact. What is DAO and why is it important? Later, you’ll read about some of the probiotics to avoid if you have Mast Cell Activation Syndrome, Histamine Intolerance, or SIBO (Small Intestinal Bacterial Overgrowth). Oksaharju, A., et al. (2011). Probiotic Lactobacillus rhamnosus downregulates FCER1 and HRH4 expression in human mast cells. World journal of gastroenterology, 17(6), 750–759. https://doi.org/10.3748/wjg.v17.i6.750 Jang, S. E., Trinh, H. T., Chung, Y. H., Han, M. J., & Kim, D. H. (2011). Inhibitory effect of Lactobacillus plantarum K-1 on passive cutaneous anaphylaxis reaction and scratching behavior in mice. Archives of pharmacal research, 34(12), 2117–2123. https://doi.org/10.1007/s12272-011-1215-8
Most probiotic strains naturally produce histamine in the body. This can cause adverse reactions in people who struggle with excess histamine or histamine intolerance. Now, let’s look at a beneficial yeast probiotic. Remember, probiotics are both bacteria and yeasts. Saccharomyces boulardii But in addition to taking a DAO enzyme, you can support Histamine Intolerance with histamine lowering probiotics.You are saving my life and my hope. And I see you doing the same for many more lost souls around here! ProBiota HistaminX Powder is a unique probiotic supplement designed for those sensitive to histamine. It excludes strains known to produce high levels of histamine in the gut. Bioflavonoids (or simply flavonoids) are a type of compound synthesized by plants. They are attributed to the potential benefits of a plant-rich diet. Compounds in this family may help support healthy inflammatory responses, cellular health, and cellular signaling. †
A healthy microbiome is essential to support your body’s response to histamine. Intestinal microbes have been shown to assist in digesting foods, produce beneficial nutrients, and train immune cells to have healthy responses to foreign invaders. When the intestinal environment is calm, the intestinal cells produce a healthy level of DAO. With adequate DAO production, a healthy level of histamine exists in the intestinal tract. † ProBiota HistaminX contains probiotic species that have been carefully selected to exclude those that are known to increase histamine in the gut. The histamine-friendly species included in this formula are delivered in a delayed release (acid resistant) capsule to ensure that the probiotics are delivered intact to the lower digestive tract. This formula helps to support the body’s microbiome and healthy digestion, and may help support healthy metabolism of ingested histamine.* BrandYou’ll also often see the genus indicated by just the first letter. For example, L. rhamnosus is the abbreviated form of Lactobacillus rhamnosus. If you have histamine intolerance, it may seem like the only way to avoid unpleasant side effects is to eliminate high-histamine foods altogether. However, a low-histamine diet can be restrictive and end up depriving your body of certain nutrients. It can also make enjoying your meals an unnecessary challenge! Let’s start with choosing a low histamine probiotic. That starts with knowing more about the types of probiotics out there. Understanding Types of Probiotics Here are some of the common “Probiotic Foods” and the high histamine probiotics often found in each.
That’s because some bacterial strains commonly found in probiotics are bacteria that produce histamine.When these bacteria start to populate the gut, they can release histamine. And you’ll want to know why some probiotics can trigger your Mast Cell Activation and make your histamine levels worse!But sometimes, probiotics are available as a powder. That can be a problem if your probiotic is not spore-based. Does your histamine response get worse when using most probiotics? Do you have histamine issues such as headaches, food intolerance, hives, or heart palpitations? Are you looking to support your gut microbiome, but aren’t sure where to start? In top of that, bringing “medicine” (as this kind of supplement/probiotic is considered by our government’s regulations) is rendered almost impossible for a normal person like me (not a pharmaceutical industry, pharmacy, or professional authorized medicine importer).
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