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Steinert HC (2011). "PET and PET-CT of lung cancer". Positron Emission Tomography. Methods in Molecular Biology. Vol.727. Humana Press. pp.33–51. doi: 10.1007/978-1-61779-062-1_3. ISBN 978-1-61779-061-4. PMID 21331927. If the hospital tests show cancer cells in your colon or rectum, you will need more tests to stage the cancer. This means finding out the size of the cancer, where it is and whether it has spread to anywhere else in the body. Chao F, Zhang H (2012). "PET/CT in the staging of the non-small-cell lung cancer". Journal of Biomedicine & Biotechnology. 2012: 783739. doi: 10.1155/2012/783739. PMC 3346692. PMID 22577296. Pacak K, Eisenhofer G, Carrasquillo JA, Chen CC, Li ST, Goldstein DS (July 2001). "6-[18F]fluorodopamine positron emission tomographic (PET) scanning for diagnostic localization of pheochromocytoma". Hypertension. 38 (1): 6–8. doi: 10.1161/01.HYP.38.1.6. PMID 11463751. The scan takes between ten and 30 minutes and is painless. Most people are able to go home soon after the scan and you can eat and drink normally. MRI scan

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Ido T, Wan CN, Casella V, Fowler JS, Wolf AP, Reivich M, Kuhl DE (1978). "Labeled 2-deoxy-D-glucose analogs. 18F-labeled 2-deoxy-2-fluoro-D-glucose, 2-deoxy-2-fluoro-D-mannose and 14C-2-deoxy-2-fluoro-D-glucose". Journal of Labelled Compounds and Radiopharmaceuticals. 14 (2): 175–183. doi: 10.1002/jlcr.2580140204. If you're claustrophobic, ask the hospital staff before the day of the scan about the possibility of having a mild sedative to help you relax. What happens during the scan Radiotracer injection

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Fratt L (July 2003). "Technology". Medical Imaging. Archived from the original on 20 November 2008. A PET scan measures important body functions, such as metabolism. It helps doctors evaluate how well organs and tissues are functioning. As with SPECT imaging, PET scan data can be reconstructed and displayed as a three-dimensional image. This is in contrast to scintigraphy, which yields planar data which can only be used to create a two-dimensional image. PET is a feasible technique for studying skeletal muscles during exercises like walking. [36] Also, PET can provide muscle activation data about deep-lying muscles (such as the vastus intermedialis and the gluteus minimus) compared to techniques like electromyography, which can be used only on superficial muscles directly under the skin. However, a disadvantage is that PET provides no timing information about muscle activation because it has to be measured after the exercise is completed. This is due to the time it takes for FDG to accumulate in the activated muscles. Azad GK, Siddique M, Taylor B, Green A, O'Doherty J, Gariani J, etal. (March 2019). "18F-Fluoride PET/CT SUV?". Journal of Nuclear Medicine. 60 (3): 322–327. doi: 10.2967/jnumed.118.208710. PMC 6424232. PMID 30042160.

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Brownell GL, Burnham CA, Hoop Jr B, Bohning DE (August 1945). Quantitative dynamic studies using short-lived radioisotopes and positron detection. Symposium on Dynamic Studies with Radioisotopes in Medicine. Rotterdam: IAEA Vienna. pp.161–172. Positron emission tomography, also called PET imaging or a PET scan, is a type of nuclear medicine imaging. While an MRI or CT scan shows how part of the body looks, a PET scan can reveal how it is functioning.While attenuation-corrected images are generally more faithful representations, the correction process is itself susceptible to significant artifacts. As a result, both corrected and uncorrected images are always reconstructed and read together. After the exam, you may need to wait until the technologist determines if more images are needed. Sometimes, the technologist takes more images to clarify or better visualize certain areas or structures. The need for more images does not necessarily mean there was a problem with the exam or that something is abnormal. It should not cause you concern. Nuclear medicine procedures can be time consuming. It can take several hours to days for the radiotracer to accumulate in the area of interest. Plus, imaging may take up to several hours to perform. In some cases, newer equipment can substantially shorten the procedure time. Prekeges, Jennifer (2012). Nuclear Medicine Instrumentation. Jones & Bartlett Publishers. ISBN 1449645372. p. 189.

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Nuclear medicine is noninvasive. Except for intravenous injections, it is usually painless. These tests use radioactive materials called radiopharmaceuticalsor radiotracersto help diagnose and assess medical conditions. They may also occasionally be combined with an MRI scan (known as a PET-MRI scan). Why PET scans are used If you have an intravenous (IV) line for the procedure, your technologist will usually remove it. The technologist will leave it in place if you are to have another procedure that same day that requires an IV line.

Ontario PET Steering Committee (31 August 2008), PET SCAN PRIMER, A Guide to the Implementation of Positron Emission Tomography Imaging in Ontario, Executive Summary, pp.iii Tell the doctor and your exam technologist about any medications you are taking, including vitamins and herbal supplements. List any allergies, recent illnesses, and other medical conditions. Alternative methods of medical imaging include single-photon emission computed tomography (SPECT), x-ray computed tomography (CT), magnetic resonance imaging (MRI) and functional magnetic resonance imaging (fMRI), and ultrasound. SPECT is an imaging technique similar to PET that uses radioligands to detect molecules in the body. SPECT is less expensive and provides inferior image quality than PET. la Fougère, C.; Rominger, A.; Förster, S.; Geisler, J.; Bartenstein, P. (May 2009). "PET and SPECT in epilepsy: A critical review". Epilepsy & Behavior. 15 (1): 50–55. doi: 10.1016/j.yebeh.2009.02.025. PMID 19236949. The concept of emission and transmission tomography was introduced by David E. Kuhl, Luke Chapman and Roy Edwards in the late 1950s. Their work later led to the design and construction of several tomographic instruments at the University of Pennsylvania. In 1975 tomographic imaging techniques were further developed by Michel Ter-Pogossian, Michael E. Phelps, Edward J. Hoffman and others at Washington University School of Medicine. [78] [79]

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PET imaging with oxygen-15 indirectly measures blood flow to the brain. In this method, increased radioactivity signal indicates increased blood flow which is assumed to correlate with increased brain activity. Because of its 2-minute half-life, 15O must be piped directly from a medical cyclotron for such uses, which is difficult. [16] It is important to remain still during the exam. Nuclear imaging causes no pain. However, having to remain still or in one position for long periods may cause discomfort.Ruggiero, A.; Holland, J. P.; Hudolin, T.; Shenker, L.; Koulova, A.; Bander, N. H.; Lewis, J. S.; Grimm, J. (2011). "Targeting the internal epitope of prostate-specific membrane antigen with 89Zr-7E11 immuno-PET". The Journal of Nuclear Medicine. 52 (10): 1608–15. doi: 10.2967/jnumed.111.092098. PMC 3537833. PMID 21908391.

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